CTN Trial Progress

Randomizations for Active Studies as of the April 11 trial Progress Report.

CTN-0060-A-1 - Enrolled 452

CTN-0069 - Enrolled 757

CTN-0079-A-1 - Enrolled 10   

CTN-0080 - Enrolled 39

CTN-0082 - Enrolled 253

CTN-0097 - Enrolled 21

CTN-0099 - Enrolled 295

CTN-0099-A-1 - Enrolled 75

CTN-0101 - Enrolled 1 

News from the Nodes

Appalachian Node

Annual Appalachian Node Meeting

West Virginia University, the University of Pittsburgh, and Penn State University held the annual Appalachian Node research meeting on February 25th & 26th in Morgantown, WV as a combined in-person and virtual event. Node Co-PIs Dr. Judith Feinberg (WVU), Dr. Jane Liebschutz (Pitt), and Co-Investigator Dr. Sarah Kawasaki (Penn St) would like to extend their thanks to the many people who attended via Zoom and to everyone who helped make the meeting a success.

Discussion centered on the ongoing fentanyl epidemic and rising methamphetamine use in the region. These issues were addressed by our two outstanding guest speakers: Todd Korthuis MD of the Oregon Health & Science University emphasized opioid and methamphetamine use in rural Oregon, and Steve Shoptaw PhD of the University of California Los Angeles gave a comprehensive overview of methamphetamine use disorder and recent advances in treatment. Node members and partners also presented on potential future research efforts on substance use disorder in the region and nationally.

Video clips of speakers and presentations will be posted on the Appalachian Node website.

Dr. Feinberg’s Recent Publications:

Hodder SL, et al. The U.S. opioid crisis and HIV: deadly synergies. The Lancet 2021 (in press).

Zibbell JE, et al. Consumer discernment of fentanyl in illicit opioids confirmed by fentanyl test strips: lessons from a syringe services program in North Carolina. Int J Drug Policy 2021 (accepted for publication).

Pollini RA, et al. A qualitative assessment of discharge against medical advice among patients hospitalized for injection-related bacterial infections in West Virginia. Int J Drug Policy 2021 (accepted for publication).

And 2 chapters from late last year:

Akhtar WZ & Feinberg J. Opioid Use Disorder and Rural America. In: The Opioid Epidemic and Infectious Diseases (Norton BL, editor). Elsevier, 2020. ISBN: 978-0-323-68328-9.

Cafardi JM & Feinberg J. The Case of Scott County: Injection Drug Use and HIV/HCV Outbreaks. In: The Opioid Epidemic and Infectious Diseases (Norton BL, editor). Elsevier, 2020. ISBN: 978-0-323-68328-9

New England Consortium

Shelly F. Greenfield, MD, MPH (McLean Hospital/Harvard Medical School) from the New England Consortium Node was the featured presenter at the annual Harvard Medical School (HMS) Hollis L. Albright, MD ’31 Symposium on Wednesday March 3, 2021. Each spring, since 2001, this endowed HMS symposium highlights scientific initiatives at Harvard Medical School. Dr. Greenfield’s talk, "Women and Addiction: From Science to Policy" was a presentation of the science underpinning a gender-specific approach to optimizing addiction prevention and recovery for women.

Gail D’Onofrio, MD, MS, FACEM, FASAM (Yale School of Medicine), one of the New England Consortium Node PIs, is presenting the opening Plenary Session at ASAM; ED-initiated Buprenorphine for Opioid Use Disorder: Should it be a choice? She is also receiving the R. Brinkley Smithers Distinguished Scientist Award. The Award recognizes and honors an individual who has made highly meritorious contributions in advancing the scientific understanding of addiction, its prevention and treatment.

Richard Saitz, MD, MPH, FACP, DFASAM (Boston University) is receiving the ASAM Educator of the Year Award. The ASAM Educator of the Year Award recognizes and honors an educator who has made outstanding contributions to ASAM’s addiction medicine education.

Jeanette M. Tetrault, MD, FACP, FASAM (Yale School of Medicine) is receiving the ASAM Training Directors Award. This award recognizes and honors an individual who has demonstrated outstanding training in the evaluation, treatment, research and teaching of substance use disorders.

Western States

Congratulations to Dr. Todd Korthuis, Western State Node MPI, on his appointment to Oregon Governor Brown’s Psilocybin Advisory Board!

In November 2020, Oregon voters approved Ballot Measure 109 allowing the manufacture, delivery and administration of psilocybin in clinical practice. The ballot measure requires a two-year period for the advisory board to recommend structural oversight and regulations for the law's implementation. Measure 109 has the potential to advance the science of mental health and addiction treatment by providing an opportunity to rigorously assess the use of psilocybin in clinical settings. Find additional information here.

From the ATTC Network

ATTC Messenger - April 2021
Introducing NIDA's Justice Community Opioid Innovation Network (JCOIN). By Tisha R. Wiley, PhD and Lori J. Ducharme, PhD (NIDA).

ATTC/NIATx Service Improvement Blog
Change Project 911: What to Do When the Idea Well Has Run Dry - Mat Roosa, LCSW-R

How Do We Successfully Implement SUD Screening and Referrals in Title X Family Planning Settings? Integration of Services is Key - Lena Marceno, MSc and Denise Raybon, MPH

Upcoming Events

April 14, 2021 (12-6pm EDT): Opioid Use in the Context of Polysubstance Use: Research Opportunities for Prevention, Treatment, and Sustained Recovery (NIDA, HEAL Initiative)
Register here!

April 26-28, 2021: Annual CTN Steering Committee Meeting
Registration now open!

June 21-24, 2021: CPDD 2021 Annual Meeting (virtual)
Registration is open!