CTN Bulletin logo
September 15, 2022 

News from NIDA

NIDA logo

Prenatal cannabis exposure associated with mental disorders in children that persist into early adolescence.

This NIDA news release reports on a new publication in JAMA Pediatrics that found that prenatal cannabis exposure following the middle of the first trimester--generally after 5-6 weeks of fetal development--is associated with attention, social, and behavioral problems that persist as the affected children progress into early adolescents (11-12 years of age). Read more here.

Increased use of telehealth for OUD services during COVID-19 pandemic associated with reduced risk of overdose.

This NIDA news release describes the results of a study published in JAMA Psychiatry that found that the expansion of telehealth services during the COVID-19 pandemic was associated with individuals staying in treatment longer and reducing their risk of medically treated overdose.

The study also found that while receiving OUD-related telehealth services was associated with better outcomes, some groups were less likely to receive those services, like non-Hispanic Black people and those living in the South. Read more here.

Marijuana and hallucinogen use among young adults reached all-time high in 2021

Marijuana and hallucinogen use in the past year reported by young adults 19 to 30 years old increased significantly in 2021 compared to five and 10 years ago, reaching historic highs in this age group since 1988, according to the Monitoring the Future (MTF) panel study. Rates of past-month nicotine vaping, which have been gradually increasing in young adults for the past four years, also continued their general upward trend in 2021, despite leveling off in 2020. Past-month marijuana vaping, which had significantly decreased in 2020, rebounded to pre-pandemic levels in 2021. Alcohol remains the most-used substance in this age group. Read more here.


CTN Trial Progress

GraphRandomizations for Active Studies as of the September 14 Trial Progress Report.

CTN-0080 - Enrolled 102

CTN-0097 - Enrolled 415

CTN-0098 - Enrolled 76

CTN-0099 - Enrolled 1130

CTN-0099-A-1 - Enrolled 88

Discontinuation - Enrolled 72
Retention - Enrolled 463

CTN-0101 - Enrolled 175

CTN-0107 - Enrolled 70

CTN-0108 - Enrolled 50

This project is supported by a grant from the National Institute on Drug Abuse to the University of Washington Additions, Drug & Alcohol Institute, but the information on this site has not been reviewed by NIDA and does not necessarily reflect the views of the Institute.

· · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · ·

Upcoming Events

Repeats name of eventWebinar: The Effectiveness & Utility of Telebehavioral (Telehealth) Services

November 2, 2022 | 11am-12:30pm PT | Register here
Sponsored by the Western States Node of the NIDA CTN and the Pacific Northwest and Pacific Southwest ATTCS

The uptake in the use of telebehavioral services since the start of the Public Health Emergency (PHE) has been swift and is significantly transforming how behavioral health services are delivered. This is encouraging, as the research base for assessing and treating mental health conditions virtually is extensive and over 60 years old. However, for substance use disorders (SUDs), the research is less extensive and more recent. Mental health and SUD treatment services provided virtually are effective and serve as viable alternatives to in-person service delivery. Patients confirm high levels of satisfaction with telebehavioral health, while practitioners report more reluctance. Nonetheless, training has been shown to build practitioners’ skills, confidence, and competency.

Using technology to facilitate clinical or recovery support sessions requires clinicians and peer support specialists to simulate real-time experiences (Hilty, 2002) that promote a therapeutic alliance (treatment) or connection (peer support). However, virtual service delivery requires some careful modification of the clinicians’ or peer support specialists’ skills to ensure engagement occurs and positive working relationships are developed.

This webinar, presented by Nancy A. Roget, MS, MFT, LADC and Maryellen Evers, LCSW, CAADAC, CMFSW, will include a brief review of: telebehavioral health research and its efficacy, strategies that promote skill development, how to create a virtual presence, resources related to guidelines and tips, and comments regarding hybrid service delivery.

1.5 CME & CE will be available.

Register here | Read more about this event here


Michael BogenshutzCCTN Webinar: Exploring the Therapeutic Potential of Psilocybin in Alcohol Use Disorder and Other Addictions

September 27, 2022 | 1:00-2:00pm PT | Register here

The presentation will provide a brief summary of findings from recent clinical research with classic psychedelics. Dr. Michael Bogenschutz will present results from a recently completed randomized controlled trial of psilocybin-assisted treatment for alcohol use disorder, including findings regarding drinking behavior, safety, and several relevant psychological outcomes.

The talk will conclude by considering possible next steps toward understanding how psilocybin and related drugs alter addictive behavior, and whether these effects can be harnessed to yield new safe and effective treatments for substance use disorders.


Repeats title of eventSAVE THE DATES: Opioid Use in Rural Communities: A 4-Part Series Addressing Implementation of Medication Treatment for Opioid Use Disorder in Clinical Settings

October 12, November 8, December 7, January 18
Sponsored by the Greater Southern California Node of the NIDA CTN and the Pacific Southwest ATTC

The dramatic increase in opioid overdose deaths across the nation, particularly in rural areas, highlights the need for rapid expansion of access to medication treatment for opioid use disorder (MOUD). The Greater Southern California Node (GSCN) of the National Institute on Drug Abuse (NIDA) Clinical Trials Network (CTN) and the Pacific Southwest Addiction Technology Transfer Center (ATTC) present a 4-part series featuring rural clinicians and clinical researchers who will share practical knowledge and skills for improving care for patients with OUD in rural settings.

The series will be hosted by Larissa Mooney, M.D. Dr. Mooney is a Professor of Clinical Psychiatry and the Director of the Addiction Psychiatry Division in the Department of Psychiatry and Biomedical Sciences at UCLA. She is also a Principal Investigator for the GSCN of the NIDA CTN.

Read more here.

· · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · ·

News from the New England Consortium Node

Edouard CoupetDr. Edouard Coupet II, MD, MS, of Yale Department of Emergency Medicine, was awarded a Diversity Supplement. The title of the study is Racial/Ethnic Disparities in Addiction Treatment Access for Opioid Use Disorder from the Emergency Department.

The emergency department (ED) represents an emerging setting to initiate medications for opioid use disorder and provide linkage to ongoing addiction treatment for Black and Latino populations with untreated OUD. Yet Black and Latino individuals with untreated OUD face significant disparities in access to ongoing addiction treatment following an ED visit. The goal of this proposal is to elicit potential targets for ED-based interventions that improve engagement in addiction treatment among Black and Latino individuals with untreated OUD. The specific aims are to: 1) conduct a qualitative study focusing on patterns of barriers and facilitators to engaging in addiction treatment among Black, Latino, and non-Latino White patients receiving ED-initiated buprenorphine treatment with a referral for continuation of OUD treatment outside of the ED and 2) evaluate differences among Black, Latino, and non-Latino White ED patients with untreated OUD on factors previously identified as predictors of worse treatment outcome, including opioid overdose, polysubstance use, major depressive disorder, and stigma, using supplemental analyses of data collected in CTN 0099. To accomplish this, we will conduct both semi-structured individual interviews of Black, Latino, and non-Latino White participants enrolled in CTN 0099 after they have completed their final 30-day assessments and supplemental analyses from data collected in CTN 0099. Study findings will inform the development of an ED-based intervention that enhances engagement in addiction treatment among Black and Latino populations subsequent to ED visit.

New from the ATTC

AATTC logoTTC Messenger, September 2022
Understanding the Patient Journey through Treatment and Recovery -- Kayla Zawislak, LSE, CADC, Addiction Policy Forum

ATTC NIATx Service Improvement Blog
Embracing Change: This Recovery Month, BHPs Should Take Steps to Recover from Burnout -- Alexander Waitt, Central East ATTC

· · · · · · · · · · · · · · · · · · · · · · · · · · · · ·

New from SAMHSA

Cover of guideAdapting Evidence-Based Practices for Under-Represented Populations

This guide focuses on research supporting adaptations of evidence-based practices for under-resourced populations. Adaptations include tailoring care, programs, and services to the cultural, social, gender, and demographic contexts of the people served to yield positive outcomes.

Cover of guideAddressing Burnout in the Behavioral Health Workforce through Organizational Strategies

Burnout is a complex issue resulting from chronic workplace stress that encompasses exhaustion, depersonalization, and reduced personal accomplishment. This guide will highlight organization-level interventions to prevent and reduce burnout among behavioral health workers.

· · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · ·

New in the CTN Dissemination Library

Journal coversSex differences in weight gain during medication-based treatment for opioid use disorder: A meta-analysis and retrospective analysis of clinical trial data. Manza P, et a. Drug & Alcohol Dependence 2022;238:109575. CTN-0030

The feasibility and utility of harnessing digital health to understand clinical trajectories in medication treatment for opioid use disorder: D-TECT study design and methodological considerations. Marsch LA, et al. Frontiers in Psychiatry 2022;13:871916. CTN-0084-A-2

Under-representation of key demographic groups in opioid use disorder trials. Rudolph KE, et al. Drug and Alcohol Dependence Reports 2022;10084 (in press). CTN-0027, CTN-0030, CTN-0051

Patient characteristics associated with opioid abstinence after participation in a trial of buprenorphine versus injectable naltrexone. Greiner MG, et al. Substance Use & Misuse 2022;57(11):1732-1742. CTN-0051

Association between treatment setting and outcomes among Oregon Medicaid patients with opioid use disorder: A retrospective cohort study. Hartung DM, et al. Addiction Science & Clinical Practice 2022;14:45. CTN-0086

Emergency department utilization for substance use disorders and mental health conditions during COVID-19. Venkatesh AK, et al. PLoS One 2022;17(1):e262136. CTN-0081

Buprenorphine & methadone dosing strategies to reduce risk of relapse in the treatment of opioid use disorder. Rudolph KE, et al. Drug and Alcohol Dependence 2022;239:109609. CTN-0027, CTN-0030, CTN-0051

· · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · ·

NIDA Racial Equity Initiative Funding Opportunity

NIDA has released new Funding Opportunity Announcements (FOAs) for the NIDA Racial Equity Initiative.

These FOAs are focused on research to advance equity for racial and/or ethnic minority populations in the U.S.

A webinar is being offered on September 26, 2022 at 3pm ET for those interested in asking questions or learning more about these FOA.

Find more information here!

Upcoming Events

Gender and Health: Impacts of Structural Sexism, Gender Norms, Relational Power Dynamics, and Gender Inequities
October 16, 2022 | 11:00am-5:00pm (virtual)
Day-long NIH virtual workshop focused on the definitions and frameworks commonly used to study structural sexism and gender norms, issues related to measurement and evaluation, interventions aimed at mitigating health disparities, and more.

2022 NIDA-NIAAA Frontiers in Addiction Research Mini-Convention
November 1-2, 2022 11am-3pm PT (virtual)
Provides a forum for presentations and discussions of current topics in neuroscience and addiction.




Published by the CTN Dissemination Library of the Pacific Northwest Node
Addictions, Drug & Alcohol Institute, University of Washington

This project is supported by a grant from the National Institute on Drug Abuse to the University of Washington Addictions, Drug & Alcohol Institute, but the information on this site has not been reviewed by NIDA and does not necessarily reflect the views of the Institute.

Unsubscribe | Subscribe