CTN Trial Progress

Randomizations for Active Studies as of the December 15 Trial Progress Report.

CTN-0080 - Enrolled 116

CTN-0097 - Enrolled 415

CTN-0098 - Enrolled 103

CTN-0099 - Enrolled 1292

CTN-0099-A-1 - Enrolled 92

CTN-0100
Discontinuation - Enrolled 103
Retention - Enrolled 610

CTN-0101 - Enrolled 190

CTN-0107 - Enrolled 98

CTN-0108 - Enrolled 64

Protocol News: CTN-0100

In November, the CTN-0100 Project Team launched a month-long BINGO challenge aimed at boosting recruitment across the 18 study sites. BINGO squares included hitting (or exceeding!) randomization targets for the month, reuniting with a missing participant, and completing internal QA.

The Adapt site from the Western States Node (pictured below, left) and the SSTAR site (right) from the New England Consortium Node were the first sites to "BINGO," just 16 days into the challenge (see photos of the winning team below)! 7 additional sites achieved "BINGO" by the end of the month. We thank all of the CTN-0100 sites for their continued diligence on this project.

Check out the BINGO sheet here!

News from the New England Consortium Node

Gail D'Onofrio, MD, MS, was awarded the 2022 American College of Emergency Physicians' (ACEP) Innovation & Excellence in Behavioral Health & Addiction Medicine Award.
David Fiellin, MD, was named the new Editor in Chief of the Journal of Addiction Medicine.

Kathryn McHugh, PhD, named Chief of Psychology at McLean Hospital.

New publication: The opioid use disorder core outcomes set (OUD-COS) for treatment research: findings from a Delphi consensus study. Karnik NS, et al. Addiction. 2022 Sep;117(9):2438-2447. Find it in the CTN Dissemination Library!

New from the ATTC Network

"Embracing Change" During COVID and Beyond by Greg Grisolano (ATTC Network). ATTC Messenger, December 2022.

Embracing Change: A System Framework for Visualizing Change by Maureen Nichols (South Southwest ATTC Director). ATTC/NIATx Service Improvement Blog, December 2022.

News from the Health Systems Node

Kelly Young-Wolff, PhD, MPH, a clinical psychologist, Kaiser Permanente Division of Research and Health Systems Node investigator who studies substance use among vulnerable populations, including pregnant women, was awarded the 2022 Young Professional Award by the American Public Health Association (APHA) Maternal and Child Health (MCH) Section.

The award was presented during the section’s luncheon at the APHA annual meeting November 7.

The Young Professional Award recognizes an MCH section member aged 40 or younger who has made a significant contribution to maternal and child health, and who has potential for making a sustained and meaningful impact on the field.

Young-Wolff was recognized for her "outstanding program of research, teaching, and mentoring," wrote Whitney Perkins Witt, PhD, MPH, past chair of the APHA Maternal and Child Health Section, in announcing the award.

Young-Wolff has used her expertise in substance use, clinical practice, social equity, and public health networks in designing and disseminating her work, building a wide network of collaborators reflecting different areas of expertise, Witt wrote, and noted Dr. Young-Wolff’s strong commitment to studying how social determinants of health impact healthcare and health outcomes.

Since her recruitment to the DOR in 2014, Young-Wolff has become a recognized expert in prenatal cannabis use and its impact on mothers and their children.

Working with a multi-disciplinary research team, she has produced work documenting increasing rates and frequency of prenatal cannabis use, along with associations between prenatal cannabis use and depression and anxiety, nausea and vomiting, and proximity to cannabis retailers.

She also worked with Kaiser Permanente Northern California clinical and operational leaders to pilot test an expanded prenatal substance use screening questionnaire that was later implemented across the region.

Read the complete press release here

News from NIDA

NIH Launches Harm Reduction Research Network to Prevent Overdose Fatalities

To address the overdose crisis in the United States, the National Institutes of Health has established a research network that will test harm reduction strategies in different community settings to inform efforts to help save lives. The harm reduction research network’s efforts will be funded by the NIH HEAL Initiative and build on existing harm reduction research, and represent the largest pool of funding from NIH to date to study harm reduction strategies to address overdose deaths.

Read more from the NIDA press release here.

Upcoming Events

Opioid Use in Rural Communities
Parts 3 and 4 of this 4-part series sponsored by the Greater Southern California Node and the Pacific SW ATTC are coming up this January and February!

Part 3: Caring for Complex Patients in Resource-Limited Communities
January 18, 2023, 12-1pm PST

Part 4: The Substance Use Disorder Workforce
February 15, 2023, 12-1pm PST

Learn more about the series and register here!