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This booklet contains an overview of the National Drug Abuse Treatment Clinical Trials Network, along with a description of each participating Node.
This brochure, intended for clinicians participating in the CTN-0013 clinical trial (MET to Improve Treatment Utilization and Outcome in Pregnant Substance Users), provides an overview of Motivational Enhancement Therapy (MET) and answers to questions participants might have about being involved in the research project.
Provides an overview of clinical trials, what they are and how they work, and then answers some commonly posed questions from participants wondering “Should I participate?” or “What questions should I ask?”
This handy brochure provides a brief description of the mission of the National Drug Abuse Treatment Clinical Trials Network (CTN), along with a list of all the participating Nodes in the Network and the location and contact information for each Node’s Regional Research and Training Centers (RRTCs) and Lead Investigators.
Contact information for each of the CTN’s four Coordinating Centers (Clinical, Data and Statistics 1 and 2, and Logistics) is also provided, along with a description of the CTN’s infrastructure, a framework that helps facilitate the CTN’s rapid testing and dissemination of science-based treatments to communities nationwide.
This brochure, intended for participants thinking about joining the CTN-0037 clinical trial (Stimulant Reduction Intervention Using Dosed Exercise), describes the aims of the study, which seeks to find out whether exercise can help people get off and stay off drugs, and what participants can expect after they sign up.
Related protocols: CTN-0037
This brochure, intended for participants thinking about joining the CTN-0044 clinical trial (Web Delivery of Evidence-Based, Psychosocial Treatment for Substance Use Disorders), describes a web-based program called Therapeutic Education System (TES) and how it can be used to help people get off and stay off drugs. Common questions participants might have are answered, including questions about compensation, what to expect from the study, and who can join.
Related protocols: CTN-0044
This 12-page brochure provides an overview of the first decade of research in the National Drug Abuse Treatment Clinical Trials Network. The CTN was started in 1999 to help bridge the gap between research and practice in the drug and alcohol abuse field, helping move evidence-based treatments into adoption in community treatment centers. The CTN’s innovative approach blends the skills and experience of community treatment providers and academic researchers in collaborative partnerships (“Nodes”) that offer patients better access to scientifically tested treatments. In the first 10 years, the CTN has fueled a cultural shift toward evidence-based care for substance abuse treatment, showing that rigorous and relevant clinical research can be carried out directly in CTPs and can address a broad range of addictive disorders. Some of the most effective protocols include those about buprenorphine, a pharmacotherapy for opiate addiction; contingency management/motivational incentives; and motivational interviewing.
The brochure also describes several CTN-related projects, such as the NIDA/SAMHSA Blending Initiative, which has developed several products to assist in the dissemination and training for some of the CTN’s successful treatment protocols, and the CTN Dissemination Library, which is a digital repository of resources and downloadable materials by and about the CTN. The CTN will continue to evolve and is poised to examine a variety of innovative approaches in its next decade, all with the ultimate goal of getting the best treatments to those who need them.
This brochure, intended for participants thinking about joining the CTN-0046 (Smoking Cessation and Stimulant Treatment Study (S-CAST)) protocol, provides an overview of the project and answers any questions participants might have. This study will compare participating clinics’ treatment as usual for stimulant dependence with a combination of treatment for stimulant dependence and smoking cessation to discover the latter’s impact on stimulant-use outcomes, outcomes for other drugs of abuse, and smoking outcomes. Research shows that rates of smoking in cocaine and methamphetamine users are 3-4 times greater than in the general population; it is hoped that this combined approach will be effective for reducing both smoking and stimulant use in participants.
Related protocols: CTN-0046
This brochure, intended for participants thinking about joining the CTN-0031 protocol (Stimulant Abuser Groups to Engage in 12-Step (STAGE-12): Evaluation of a Combined Individual-Group Intervention to Reduce Stimulant and Other Drug Use by Increasing 12-Step Involvements) provides an overview of the project and answers any questions participants might have.
This study will evaluate the degree to which a combined group and individual intervention that also uses recovery mentors improves substance-related outcomes compared to treatment as usual.
Related protocols: CTN-0031
NIDA’s National Drug Abuse Clinical Trials Network (CTN) improves the quality of drug abuse treatment throughout the country by overcoming a major challenge — the slow process of transforming research findings into proven treatments that are available and feasible in community practice settings where most people seek help for drug abuse or addiction. This four-page pamphlet provides an overview of the CTN from its inception to the present, including key findings from several of its completed protocols, a discussion of the CTN’s impact on communities at the local, regional, and state level, and information about the CTN Dissemination Library, a free public resource containing CTN’s research findings and other materials related to the project.
This brochure, intended for participants thinking about joining the CTN-0027 clinical trial (Starting Treatment with Agonist Replacement Therapies), answers questions about who can participate and what happens if you join, and provides information about the medication used in the project, buprenorphine naloxone (Suboxone).
Related protocols: CTN-0027
This seven-page informational brochure provides general guidelines for clinicians and researchers who will be interviewing research participants in the CTN. These guidelines include tips on asking sensitive questions, protecting a participant’s confidentiality and privacy, dealing with a difficult participant, and interviewer safety.
This brochure, intended for participants thinking about joining the CTN-0030 (Prescription Opioid Addiction Treatment Study (POATS)) protocol, provides an overview of the project and answers any questions participants might have. The main objective of this trial is to identify effective treatment regimen for sublingual Buprenorphine/Naloxone (BUP/NX) in patients dependent on prescription opioids. The first phase will assess the currently prevailing 1-month detoxification practice. The second phase will compare the effectiveness of standard medical (BUP/NX) management and medical management (BUP/NX) enhanced by intensive individual drug counseling (IDC) in those patients that were not successful in the previous phase.
Related protocols: CTN-0030
This brochure, intended for clinicians thinking about participating in the CTN-0020 clinical trial (Job Seekers Training for Patients with Drug Dependence), describes the interventions the study will be investigating, how study therapists will be chosen, and what participants can expect if they become study therapists themselves.
Related protocols: CTN-0020
This brochure, intended for participants thinking about joining the CTN-0017 clinical trial (HIV and HCV Intervention in Drug Treatment Settings), provides an overview of the study’s aims, a description of what participation will involve, and information about compensation.
Related protocols: CTN-0017