Search the Library
NOTE: This is a new search platform (as of May 2026). If you do a search and don’t get the results you were expecting, please email us at ctnlib@uw.edu to let us know? (If possible, please share your exact search strategy. Thank you!)
Enter keywords and hit Enter (or click the magnifying glass) to search. You can then also select document type or subject/topic to narrow results further (or just use those for searching without a keyword). Results display below this search form.
Document types
Subjects
- CTN-#### format for protocols (CTN-0001, e.g.)
- “exact phrase” (if phrase is not found, it will return results that contain all terms
- word1 NOT word2
- word1 word2 (finds both words)
- Click title to access full-text
- “Show details” reveals abstract & other info
- Checkboxes select items for copy/pasting or printing
- Need help getting a copy of a journal article?
Email ctnlib@uw.edu
Search results
Buprenorphine is one of three medications (methadone and naltrexone being the other two) approved for use to treat opioid use disorder. It is available as a film or tablet, and more recently as two long-acting extended-release injectables. Sublocade™ was first to be approved by the FDA in November 2017. More recently, in May 2023, Brixadi™ received approval. In January 2024 it was added to the WA state Medicaid formulary.
Fewer clinicians have experience using Brixadi™ than Sublocade™. The videos, podcast, and information sheets on this page are intended to aid prescribers in their conversations with patients interested in these buprenorphine options.
Watch the symposium recording.
The Ohio Valley Node hosted CTN Director Dr. Betty Tai and NIDA senior advisor Geoffrey Laredo on November 27-28 to visit OVN offices and associated treatment programs at the University of Cincinnati. The visit included a public symposium on Tackling the Ohio Opioid Crisis: Harnessing the Power of Science to Break the Cycle, for which Dr. Tai presented the keynote address “Collision Of PAIN & OPIOID Epidemics: Challenges & Solutions.”
Over 400 attendees received information on efforts by local legislative bodies, state-level policy makers, academic health systems, providers, and researchers to more effectively address the current opioid crisis in Ohio in the OVN!
The Patient-Centered Outcomes Research Institute (PCORI) is an independent, nonprofit organization created by the Affordable Care Act in March 2010 that funds comparative effective research to answer important real life questions. In 2014, the PCORI Advisory Panel on Assessment of Prevention, Diagnosis, and Treatment Options prioritized 14 new research topics, including Treatment Options for Substance Abuse.
The National Drug Abuse Treatment Clinical Trials Network (CTN) sponsored this workshop for all NIDA investigators interested in learning how to apply for PCORI funding. It was also broadcast via webinar to remote participants. The workshop was co-chaired by Betty Tai, Director, CCTN and Redonna Chandler, Acting Director, DESPR. The goal of the workshop was to provide technical assistance to NIDA grantees regarding PCORI funding opportunities, given that PCORI identified treatment options for opioid substance abuse as a high-priority research topic, and that their funding process is different from the NIH process. The agenda included a presentation from PCORI staff summarizing PCORI’s objectives, priorities, available funding, and application process. NIDA researchers discussed the state of the science regarding opioid substance abuse and presented experiences with the PCORI funding/review process. Presenters included: Dr. Joe Selby and Dr. David Hickam, PCORI, Dr. Walter Ling, UCLA, Dr. Adam Brooks, TRI, Dr. Cynthia Campbell, Kaiser Permanente, and Dr. Jay Ford, Univ. of Wisconsin.
View the workshop agenda and speaker bios. Slides from the presentations are available below. (Additional PCORI-related resources are available in the sidebar to the right.)
Overview of PCORI — David Hickam, MD, MPH; Bryan Luce, PhD, MS, MBA; Joe V. Selby, MD, MPH.
Opportunities to Test Effective Opiate Treatments — Walter Ling, MD
Engaging Patients and Clinicians to Improve Patient-Centered Treatment Outcome: Stakeholders’ Substance Use Research and Treatment Information Exchange — Walter Ling, MD
Prescription Opioid Management in Chronic Pain Patients: A Patient-Centered Activation Intervention — Cynthia Campbell, PhD, MPH
Review Experience — Jay Ford, PhD
This Blending Initiative Workshop focused on clinical management of prescription opioid use disorders and screening and brief intervention for substance use disorders in the emergency department. [view flyer | view agenda]
View videos in order by clicking on player window (to advance to the next video in the playlist, hover over the screen and click the >>| button at the bottom), or individually using the links below.
Session 1: Clinical Management of Prescription Opioid Use Disorders (moderator: Andrew J. Saxon, MD)
- Introduction to the Workshop — Andrew J. Saxon, MD and Megan L. Ranney, MD, MPH
- ACEP Clinical Policy: Review and Implementation of the Clinical Guideines — Knox H. Todd, MD, MPH, FACEP
- Hard Conversations: Addressing Patients with Chronic Pain — Kavita M. Babu, MD, FACEP, FACMT
- Facilitation Through Technology: Prescription Drug Monitoring Programs — Edward W. Boyer, MD, PhD
Session 2: Panel Discussion of Working and Successful Models
- North Carolina Emergency Department Care Coordination Trial — Chris L. Ringwalt, DrPH
- A Randomized Controlled Trial of Citywide Emergency Department Care Coordination — Darin E. Nevin, MD, MS
- Guidance for Opioid Prescribing: Lessons Learned from the NYC Experience — Lewis S. Nelson, MD, FACEP
- Rural Strategy to Reduce Drug Diversion — John J. Graykowski, MPAS, PA-C
- Morning Panel Discussion
Luncheon Roundtable Discussion: Implementation and Application of ACEP Clinical Policy Critical Issues in the Prescribing of Opioids for Adult Patients in the Emergency Department. Moderated by Lewis S. Nelson, MD, FACEP and Knox H. Todd, MD, MPH, FACEP
Session 4: Screening and Brief Intervention for Substance Use Disorders (moderator: Megan L. Ranney, MD, MPH)
- Overview of Screening and Brief Intervention in the Emergency Department — Gail D’Onofrio, MD, MS, FACEP
- Addressing Patients with Comorbid Conditions — Douglas F. Zatzick, MD
- Using Technology to Facilitate SBIRT: Web and Computer-Based Screening and Brief Intervention — Rebecca M. Cunningham, MD
Session 5: Panel Discussion of Working and Successful Models
- Training Trauma Center Clinicians to Perform Screening and Brief Intervention: Results from a National Training Effort — Christopher W. Dunn, PhD
- Statewide Dissemination of Emergency Room Screening and Brief Intervention: Lessons Learned Blending Research and Practice — Edward Bernstein, MD, FACEP
- Implementation of a Screening and Brief Intervention Program in a Large Safety-Net Trauma Center — Kerryann B. Broderick, MD, BSN, FACEP
- Screening and Brief Intervention Strategies for Emergency Nurses — Patricia K. Howard, PhD, RN, CEN, CPEN, NC-BC, FAEN
- Afternoon Panel Discussion
In 2012, the CTN Web Seminar Series introduced research staff to the use of social media in trials and the tools available in the market. Building on that training, this 60-minute webinar, produced by the National Drug Abuse Treatment Clinical Trials Network (CTN) Clinical Coordinating Center for CTN members and the public, focuses on applying that knowledge and incorporating guidelines for use in clinical trials.
Objectives for this webinar include:
- Understanding organizational and IRB guidelines regarding the use of social media in the conduct of research.
- Learning how to use social media tools to recruit, engage, and follow-up with research participants.
- Reviewing what elements to consider when drafting a social media strategy for your research project.
- The target audience is research staff interested in using social media in the conduct of clinical trials.
Presented by Erin L. Winstanley, PhD (University of Cincinnati, OV Node) and Gloria M. Miele, PhD (Columbia University, GNY Node)
Additional Resources:
[Note: the CD version of this product is no longer available. Factsheets and links to additional resources may still be available at the link provided.]
This new CD-ROM features copies of the three previous buprenorphine-related Blending Products (Buprenorphine Treatment, Short-Term Opioid Withdrawal Using Buprenorphine, and Buprenorphine Treatment for Young Adults), bundled together with the new Prescription Opioid Addiction Treatment Study (POATS) product.
The new POATS product includes a clinician training program and manual, PowerPoint presentation, resource list, fact sheets, and additional materials to help clinicians implement and promote buprenorphine treatment in their practices.
This CD-ROM compilation includes resources in a variety of formats, including training manuals (PDFs), PowerPoint presentations, short video clips, research articles, and other resources.
This one-day conference was designed to benefit front-line clinical staff delivering addiction treatments in Texas. Speakers presented on a wide variety of topics, focusing primarily on the scientific basis for selected pharmacological and behavioral evidence-based practices, providing concrete examples, experiential learning experiences, and practical implementation guidance.
Presentations:
Exercise for the Treatment of Addiction, Madhukar H. Trivedi, M.D.
Motivational Interviewing: Implementing an Evidence-Based Practice, Mary M. Velasquez, PhD.
Conducting Research in a Community-Based Setting: Challenges and Rewards, A. Rebecca Crowell, MEd, LPC, LCDC; Douglas Denton, MA, LCDC, LCCA
Addictions Pharmacotherapy, Thomas Kosten, MD
CTN-0030 POATS Blending Review, Jennifer Sharpe Potter, PhD, MPH
Evidence-Based Treatments for Traumatic Stress and Addictions, Denise Hien, PhD
HIV Blending Product, Richard Spence, PhD
Research into Practice – Motivational Incentives, Michael Levy, PhD
Brief Strategic Family Therapy, Joan Muir, PhD
Researchers involved in the CTN protocols NIDA-CTN-0006 and NIDA-CTN-0007 (Motivational Incentives for Enhanced Drug Abuse Recovery in Drug Free Clinics and Methadone Clinics) have shown that motivational incentive programs using low-cost reinforcement (prizes, vouchers, clinic privileges, etc.), delivered in conjunction with onsite urine screening promotes higher rates of treatment retention and abstinence from drug abuse. This Blending Team product focuses on informing the field about successful approaches in the use of motivational incentives (also referred to as contingency management). The package includes an instructional CD-ROM, loaded with a video featuring conversations from top researchers to clinicians to patients in the field of addiction and recovery; sample documents that are customizable to your needs; PowerPoint presentations; research articles; and various additional resources. The PAMI Product was distributed to Research Utilization Committee (RUC) members in May 2007. It can also be downloaded from the ATTC web site.
This product was updated in 2011, providing tools designed to build awareness of Motivational Incentives as an effective therapeutic strategy within the addiction treatment field. It has been combined with two other MI Blending Team Products, MI:PRESTO and MIIS, to form a “Motivational Incentives (MI) Package.” MIIS has been discontinued; the other two products can be found here: https://collaborativeforhealth.org/bettertxoutcomes/.
Related protocols: CTN-0006, CTN-0007
This workshop, the third dissemination workshop organized by the CTN Research Utilization Committee (RUC), highlighted different methods CTPs have used to disseminate evidence-based treatment into their practice settings. Speakers from a number of community treatment providers presented at the workshop, which focused primarily on smoking cessation and implementation of the Matrix Model.
Presentations included:
Nicotine Replacement Prescribing Trends in a Large Psychiatric Hospital, Before and After Implementation of a Hospital-Wide Smoking Ban by Antoine Douaihy, MD, University of Pittsburgh School of Medicine, Pennsylvania, ATS Node
Recovery Network of Programs, Inc. (RNP) Tobacco Dependence Treatment Pilot by John Hamilton, LMFT, LADC, Regional Network of Programs, Inc., Connecticut, NEC Node
We Still Haven’t Come a Long Way, Baby! Smoking Cessation Efforts in an Oregon CTP by Lucy Zammarelli, MA, Willamette Family, Inc., WS Node; and Barbara Tajima, Institute for Health Policy Studies, UCSF, WS Node
Matrix Intensive Outpatient Treatment with Adolescents by Martin Moskowitz, LCSW and Seamus McEntee, LMSW, Mineola Community Treatment Center, NSLIJ, New York
The Matrix Model of Intensive Outpatient Treatment by Jeanne Obert, MFT, MSM, Matrix Institute on Addictions, California
This workshop, organized by the CTN Research Utilization Committee, highlighted different methods CTPs have used to disseminate evidence-based treatment into their practice settings. Speakers from a number of CTN Community Treatment Providers (CTPs) presented at the workshop on topics ranging from training clinicians in teleconferencing technology, to treatment systems improvement projects, to implementation of an HIV rapid testing protocol.
The workshop began with opening remarks from Harold Perl, PhD, of the NIDA Center for the Clinical Trials Network. Presentations included:
Implementing Seeking Safety — Pat Penn, PhD, Amy Tilley, PsyD, Wendy Layne, MA. La Frontera Center, Inc., CA/AZ Node
Dissemination of Project WORTH in a Residential Treatment Program for Women and Children — Susan M. Gordon, PhD, Myriah Jackson, Seabrook House, DV Node.
Increasing Retention Using Motivational Incentives — Tracy Schulden, Universal Counseling Services, MA Node
Real World Training and Implementation: The Community Reinforcement Approach — John G. Gardin II, PhD, ADAPT, Inc., OR/HI Node.
Research Meets Practice and Beyond: Clinical Implementation of HIV Rapid Testing — Louise Haynes, MSW, and Beverly Holmes, MSW, LRADAC, SC Node.
Creating an MI Culture: The “Nuts and Bolts” Experience — D. Michael Davis, ChangePoint, Inc., OR/HI Node
Training Clinicians in Motivational Interviewing Using Teleconferencing Technology — Bruce Goldman, LCSW, CASAC, North Shore-Long Island Jewish Health System, LI Node and Kenneth Carpenter, PhD, New York State Psychiatric Institute, LI Node
Dallas Coalition for Treatment Improvement: A Sudden Rise in Heroin Use Among Adolescents and Young Adults Served as a Call to Action and Inspired this Treatment Systems Improvement Project — Doug Denton, Homeward Bound, TX Node.
In addition to high rates of alcohol and drug use, Native Americans have high rates of suicide, homicide, and accidental death. These problems may be the result of “historical trauma,” according to many clinicians and researchers in the Native American community. In July of 2008, the California-Arizona Node of the National Drug Abuse Treatment Clinical Trials Network (CTN) hosted a day-long conference titled, “Historical Trauma: Healing Approaches in Native American Communities.” The conference was funded by a supplement from NIDA and featured presentations covering both theoretical discussions and research findings on historical trauma, as well as clinical approaches by frontline clinicians. Nearly 170 participants attended from across the western states, including California, Oregon, Washington, Arizona, and New Mexico.
- Introduction & Welcome (3:12)
Carmen L. Masson, PhD and James L. Sorensen, PhD, University of California, San Francisco (CA/AZ Node)
View online - Healing the Historical Trauma Response (61:00)
Maria Yellow Horse Brave Heart, PhD, Columbia University School of Social Work, Takini Network
View online - Holistic System of Care for Native Americans in an Urban Environment (30:01) Ethan Nebelkopf, PhD, San Francisco Family & Child Guidance Clinic, Native American Health Center, Oakland, CA
View online - Afflictions of Firewater and The Sword: Implications of Historical Trauma in Urban Native American Communities (24:24)
Michele Maas, MSW, San Francisco Family & Child Guidance Clinic, Native American Health Center, Oakland, CA
View online - Historical Trauma and Indigenist Stress-Coping Processes: Preliminary Research Findings from the HONOR Project (43:28)
Karina Walters, PhD, MSW, University of Washington School of Social Work, Indigenous Wellness Research Center.
View online - Cultural and Traditional Healing Approaches for Urban Native Americans (42:45)
Nelson Jim, MFT, San Francisco Department of Public Health
View online - The Four Generation Solution (26:15)
Theda New Breast, MPH, New Breast Consultants, Babb, Montana
View online - Re-Viewing Historical Trauma: Bridging Scientific Skepticism & Colloquial Claims (39:19)
Joseph P. Gone, PhD, University of Michigan, Department of Psychology
View online - Developing Evidence-Based Substance Abuse Treatments for Native American Communities: The Role of Historical Trauma (37:47)
Panel Discussion
View online
The primary goal of this Blending Team product is to create awareness and build knowledge about buprenorphine among multidisciplinary addiction professionals. The materials include information designed to increase motivation for bringing buprenorphine to local communities, as well as information about what to expect when someone is treated with this medication. Additionally, materials discuss legislation that permits office-based buprenorphine treatment, the science of addiction, the mechanism of buprenorphine, patient selection issues, and various patient, counseling, and therapeutic issues.
The Buprenorphine Awareness Blending Team package contains: the Training Guide for the 6-hour training, an informational brochure about the product, and two CDs. The first CD contains the PowerPoint presentation for the training, electronic copies of the Training Guide and brochure, and a draft version of an annotated bibliography about Buprenorphine. The second CD contains a video entitled, “Put Your Smack Down! A Video about Buprenorphine” (used in Module VI of the training) and an online course developed by the Central East ATTC called “Buprenorphine Treatment of Opioid Addiction: A Guide for Counselors.” Each of these items can also be downloaded from the ATTC web site.