Search the Library
NOTE: This is a new search platform (as of May 2026). If you do a search and don’t get the results you were expecting, please email us at ctnlib@uw.edu to let us know? (If possible, please share your exact search strategy. Thank you!)
Enter keywords and hit Enter (or click the magnifying glass) to search. You can then also select document type or subject/topic to narrow results further (or just use those for searching without a keyword). Results display below this search form.
Document types
Subjects
- CTN-#### format for protocols (CTN-0001, e.g.)
- “exact phrase” (if phrase is not found, it will return results that contain all terms
- word1 NOT word2
- word1 word2 (finds both words)
- Click title to access full-text
- “Show details” reveals abstract & other info
- Checkboxes select items for copy/pasting or printing
- Need help getting a copy of a journal article?
Email ctnlib@uw.edu
Search results
Community Based and Tribally Based Participatory Research (CBPR/TPR) are approaches that can be successful for developing ethical and effective research partnerships between academic institutions and Tribes and Native organizations. The NIDA Clinical Trials Network funded a multi-site, exploratory study using CBPR/TPR to begin to better understand substance abuse issues of concern to some Tribes and Native organizations as well as strengths and resources that exist in these communities to address these concerns. Attention was paid to the development and maintenance of research partnerships in each of the sites. Each of the five partnerships is briefly described, and common as well as unique challenges and successes are identified. A summary of the common themes for developing these collaborative research efforts is provided.
Conclusion: True, collaborative research partnerships require a great deal of time and effort in order to develop mutual trust, understanding, knowledge, and collaboration that will guide research that is rigorous as well as ethical, effective, and culturally appropriate. As AIAN communities become increasingly sophisticated partners in, and consumers of, research, CBPR and TPR are emerging as effective, ethical, culturally appropriate, and acceptable approaches. This can serve to improve the science we engage in with AIAN communities, add to the scarce literature regarding AIAN communities, and better serve AIAN communities in addressing health disparities and improving health.
Related protocols: CTN-0033-Ot
Despite the billions of dollars spent on health-focused research and the hundreds of billions spent on delivering health services each year, relatively little money and effort are directed toward investigating how best to connect the two. This results in missed opportunities to assure that research findings inform and improve quality across healthcare in general and for addiction prevention and treatment in particular. There is an asymmetrical focus that favors the identification of new interventions and neglects the implementation of science-based knowledge in actual practice. The consequences of that neglect are severe: significantly diminished progress in research on how to implement treatments that could improve the lives of persons with addiction problems, their families, and the rest of society. This commentary proposes three interrelated strategies for improving the implementation process. First, develop scientific tools to understand implementation better, by expanding investigations on the science of implementation and broadening approaches to the design and execution of research. Second, nurture and support a collaborative implementation workforce comprised of scientists and on-the-ground practitioners, with an explicit focus on enhancing appropriate incentives for both. This includes adding relevance to research right from the start, something protocol CTN-0033 (Methamphetamine and Other Drugs in American Indian and Alaska Native Communities) did by collaborating with partners in more than a dozen American Indian/Alaska Native communities. As the collaborations matured over time, other community-specific goals and activities were shaped by the expressed needs and desires of each local community. Third, pay closer attention to crafting research that seeks answers that are most relevant to clinicians’ actual needs, primarily by ensuring that the anticipated users of the evidence-based practice are full partners in developing the questions right from the start.
Related protocols: CTN-0033-Ot
The Methamphetamine and Other Drugs (MOD) in American Indian and Alaska Native communities (AIAN) project grew from NIDA?s commitment to reducing health disparities with a specific emphasis on a better understanding of the epidemiology and treatment of drug abuse, and its health consequences in minority populations in general, and AIAN communities in particular. Because few data exist on methamphetamine and other drug use in AIAN communities, NIDA’s National Drug Abuse Treatment Clinical Trials Network (CTN) funded several exploratory and developmental projects in order to develop collaborative research partnerships with AIAN communities. Each participating Node has specific processes in place for reporting and disseminating research findings that require Tribal approval from its respective research partners and findings from these projects will be presented in future publications and at professional meetings — in full partnership with our community research partners.
The purpose of this brief report is to describe the process followed by each of the Nodes as they have developed their research partnerships with AIAN communities; lessons learned and recommendations for others interested in ethical research with AIAN communities are also presented.
Related protocols: CTN-0033-Ot, CTN-0033-OT-1, CTN-0033-Ot-2, CTN-0033-Ot-3, CTN-0033-Ot-4, CTN-0033-Ot-5