News from the Ohio Valley Node

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IMPROVE Studies in Progress! 

In October 2023 the NIH IMPROVE initiative approved funds to conduct four projects under the overall leadership of Dr. John Winhusen, current Lead Investigator of the CTN 0080 MOMs study.  CTN investigators are preparing to conduct three research studies and one dissemination activity, described below: 

CTN 0150: Personally-Tailored Opioid-overdose and Medication for opioid use disorder (MOUD) Education (TOME; LI – Winhusen, OVN): This study is an intent-to-treat, open-label, randomized controlled trial planning to (1) evaluate the ability of TOME to increase MOUD and opioid-overdose knowledge in Pregnant and Post-partum (PP) persons; and (2) evaluate the ability of TOME to decrease MOUD-related internalized stigma and expected difficulty in avoiding drug use. 

CTN 0080 A-1: Successful Recruitment And Retention In A Randomized Controlled Trial Of Pregnant and Post-Partum People With Opioid Use Disorder (SUCCESS Study; LI – Smid, GIN). This ancillary study plans to perform qualitative interviews to identify successful strategies, facilitators, and barriers to recruiting pregnant individuals with opioid use disorder (OUD) and retaining them through the first year postpartum in the MOMs trial.. 

CTN 0080 A-2: Promoting Research with Mothers receiving OUD Treatment; a focus on Equity (PRoMOTE; LI – Schiff, NEC Node). This ancillary study plans to apply mixed-methods to investigate facilitators and barriers to treatment initiation of medications to treat opioid use disorder (MOUD), trial engagement, and study retention in CTN-0080, with a focus on race and equity.  

CTN 0080 A-3: Improved Messaging Strategies for MOUD For Underserved Populations Of Pregnant And Postpartum Individuals With OUD (LI – Kropp, OVN). This project (not a research study) plans to develop innovative and meaningful education/messaging strategies that will target areas such as (1) addiction disease & NOWS, (2) the role of medications in the management of OUD and overdose prevention, (3) stigma and health system mistrust, and (4) PP persons rights to treatment. This project plans to involve researchers, patients, and community advisors to develop products specific to the target population (Hispanic, Black, and Native PP women, and those living in rural areas). 

Center for Addiction Research (CAR) Summer Speaker Series coming!   

The OVN’s UC CAR invites CTN personnel to attend three upcoming presentation highlighting cutting-edge addiction research and community collaborations: 

  • Wednesday, June 12, 2024 – Risk Reduction in Human Trafficking and Substance Use Disorders:  Bringing Education, Testing, and Treatment to the Community (Caroline Freiermuth, MD, MHS, LeAnn Sanson, Director, Weightless Anchor) 
  • Wednesday, July 10, 2024 – A Unique, Co-designed Family-Based Therapy for Marginalized Women with Opioid Use Disorder and Justice-Involvement (Aaron Murnan, PhD, LMFT, Gwen England, MS) 
  • Wednesday, August 14, 2024 – Social and Psychosocial Determinants of Treatment Response and Recovery Among Black Adults Who Use Substances (Kathy Burlew, PhD, Simeon Goodwin, PhD) 

Learn more about the CAR Summer Speaker Series here!

One credit hour of Ohio continuing education credit will be offered in social work, counseling, (Ohio CSWMFT Social Work Provider RSXX038702 & Counselor Provider RCX012101), and psychology for each session.  Details for requesting CE credit will be provided at the completion  of each session.