Update on CTN-0097: Primary Outcomes Article Published!

The primary outcomes article for CTN-0097, Surmounting Withdrawal to Initiate Fast Treatment with Naltrexone (SWIFT): Improving the Real-World Effectiveness of Injection Naltrexone for Opioid Use Disorder (NIH HEAL Initiative), is now available!

Published in JAMA Network Open, the findings from the study suggest that starting people with opioid use disorder (OUD) on extended-release injectable naltrexone (XR-naltrexone) within 5-7 days of seeking treatment is more effective than the standard treatment method of starting within 10-15 days, but requires closer medical supervision.

This rapid treatment protocol could make XR-naltrexone more viable as a treatment option for OUD, as the longer waiting period was a significant barrier to implementation of XR-naltrexone for many patients.

Read the JAMA Network Open paper | Read the NIDA News Release about it