Models for implementing emergency department-initiated buprenorphine with referral for ongoing medication treatment at emergency department discharge in diverse academic centers.

There has been a substantial rise in the number of publications and training opportunities on the care and treatment of emergency department (ED) patients with opioid use disorder over the past several years. The American College of Emergency Physicians recently published recommendations for providing buprenorphine to patients with opioid use disorder, but barriers to implementing this clinical practice remain. This paper describes models for implementing ED-initiated buprenorphine at 4 diverse urban, academic medical centers across the country as part of a federally funded effort termed “Project ED Health” (protocol CTN-0069). These 4 sites successfully implemented unique ED-initiated buprenorphine programs as part of a comparison of implementation facilities to traditional educational dissemination on the uptake of ED-initiated buprenorphine. Each site describes the elements central to the ED process, including screening, treatment initiation, referral, and follow-up, while harnessing organizational characteristics, including ED culture. Finally, the paper discusses common facilitators to program success, including information technology and electronic medical record integration, hospital-level support, strong connections with outpatient partners, and quality improvement processes.

Related protocols: CTN-0069

Categories: Buprenorphine, Emergency departments, Opioid use disorder, Pharmacological therapy
Tags: Article (Peer-Reviewed)
Authors: Whiteside, Lauren K.; D'Onofrio, Gail; Fiellin, David A.; Edelman, Jennifer; Richardson, Lynne; O'Connor, Patrick; Rothman, Richard E.; Cowan, Ethan; Lyons, Michael S.; Fockele, Callan E.; Saheed, Mustapha; Freiermuth, Caroline; Punches, Brittany E.; Guo, Clara; Martel, Shara; Owens, Patricia H.; Coupet, Edouard Jr.; Hawk, Kathryn F.
PMCID: PMC9588652
PMID: 35752520
Source: Annals of Emergency Medicine 2022;80(5):410-419. [doi: 10.1016/j.annemergmed.2022.05.010]