CTN-0095: Clinic-Randomized Trial of Clinical Decision Support for Opioid Use Disorders in Medical Settings (COMPUTE 2.0)

Rebecca Rossom, MD, MSCR
Lead Investigator

HealthPartners Institute for Education & Research

Gavin Bart, MD, PhD, FACP, FASAM
Lead Investigator

Addiction Medicine
Minneapolis Medical Research Foundation

There is a significant treatment gap between patients diagnosed with OUD and those who seek treatment, and only a small proportion of those seeking treatment receive MOUD. Primary care is the most common point of healthcare contact in the US and is an important venue to address stigma, improve access to treatment, and improve quality of care. Over the past decade, electronic health record (EHR)-linked web-based point-of-care clinical decision support (CDS) systems designed to improve quality of chronic disease care have become increasingly sophisticated and successful. A web-based and electronic health record (EHR)-integrated OUD clinical decision support (CDS) system to offer expert guidance to primary care providers (PCPs) on the diagnosis and management of OUD was developed and piloted. This project will implement the OUD clinical decision support system in three large diverse health care systems and randomize a minimum of 30 clinics to receive the OUD-CDS intervention or usual care (UC). The project will evaluate the impact of OUD CDS on practice process measures and patient outcomes. The study will also prepare for scalability and dissemination by evaluating facilitators and barriers to implementation, determining the costs of implementation and maintenance, and assessing the short-term cost impacts of the OUD-CDS.

Funded by the NIH HEAL InitiativeSM.

    Node Involvement

    Lead Node(s):

  • Northstar Node

  • All Participating Nodes:

  • Northstar Node