Brief report: Meth, tranq, gas station heroin & other drugs complicating addiction treatment.

 Background and objectives: Patients using fentanyl have worse treatment outcomes; however, little is known about other drugs that complicate treatment.

Methods: A national survey (n = 396) was conducted for CTN-0135 using a random sample of clinicians waivered to prescribe buprenorphine in the United States. This study reports the results of a single survey item on clinicians’ perceptions of other drugs, besides IMF, complicating treatment.

Results: Clinicians reported methamphetamine (86.4%), synthetic cannabinoids (42.7%), and xylazine (41.4%) were complicating treatment; reports varied by geographic region.

Conclusions and scientific significance: Rapid clinician surveys can provide real-time data on changing patterns of drug use’s impact treatment outcomes.

Related protocols: CTN-0135

Categories: Buprenorphine, Fentanyl, Methamphetamine, Opioid use disorder, Synthetic cannabinoids, Xylazine
Tags: Article (Peer-Reviewed)
Authors: Winstanley, Erin L.; Liebschutz, Jane M.; Murray-Krezan, Cristina •Switzer, Galen E.; Nash, Samantha; Kawasaki, Sarah
PMID: 41741932
Source: American Journal on Addiction 2026 (in press). [doi: 10.1111/ajad.70151]