CTN-0010-A-2: Comorbid Conditions in Adolescents with Opioid Versus Alcohol/Marijuana Use Disorders

Geetha Subramaniam, MD
Lead Investigator
Mountain Manor Treatment Center
Johns Hopkins University

The purpose of this study was to determine if adolescents with opioid use disorder (OUD) have more co-morbidity than adolescents with marijuana and/or alcohol use disorders.  In the study, we assessed substance use disorder diagnoses, psychiatric diagnoses, HIV-risk behaviors, and illegal acts.  94 adolescents (ages 14-18 years) with a current OUD and 74 adolescents with a current non-OUD cannabis/alcohol use disorders were recruited from admissions, predominantly residential, to Mountain Manor, a substance abuse treatment program in Baltimore, Maryland.  Participants were assessed cross-sectionally using standardized interviews and self-report to determine group differences on demographic, substance use, psychiatric and HIV-risk behaviors.

Primary Findings

The study confirmed that adolescents with opioid-use disorder evidenced greater impairment in academic, more substance use, more depressive symptoms, and higher IDU-related HIV-risk than adolescents with marijuana and/or alcohol use disorders.

Results Article: Subramaniam G, et al. Clinical characteristics of treatment-seeking adolescents with opioid versus cannabis/alcohol use disorders. Drug and Alcohol Dependence 2009;99:141-149. [get article]

    Node Involvement

    Lead Node(s):

  • Mid-Atlantic Node

  • All Participating Nodes:

  • Mid-Atlantic Node