What’s New in the CTN?

Updates from the NIDA National Drug Abuse Treatment Clinical Trials Network. Want to share some news about your protocol, node, publications or presentations, or other CTN-related work here and/or in the CTN Bulletin? Email us at ctnlib@uw.edu!

News from the Appalachian Node

Node News

The Appalachian Node has two new publications to report: Bulls HW, Hamm M, Wasilewski J, Olejniczak D, Bell SG, Liebschutz JM. “To prescribe or not to prescribe, that is the question”: Perspectives on opioid prescribing for chronic, cancer-related pain from clinicians who treat pain in survivorship. Cancer. 2024 Apr 3. doi: 10.1002/cncr.35299. PMID: 38567685. Jennings LK, Lander L, Lawdahl T, McClure EA, Moreland A, McCauley JL, Haynes L, Matheson T, Jones R, Robey TE, Kawasaki S, Moschella P, Raheemullah A, Miller S, Gregovich G, Waltman D, Brady KT, Barth KS. Characterization of peer…

CTN Youth SIG Webinar, July 19, 2024, 11am ET

CTN Youth SIG: Upcoming webinar

The CTN Youth SIG is pleased to invite you to an upcoming presentation with two invited speakers: Presenters: Jesse D. Hinckley, MD, PhD and Chris Hammond, MH, PhD Friday, July 19th, 2024 (11:00 a.m.–12:00 p.m. ET) Join Zoom Meeting:https://dartmouth.zoom.us/j/94616304667?pwd=MHhGUjBzcmVNUVVlV1IyT0hjR3YrUT09 Meeting ID: 946 1630 4667Passcode: 047757One tap mobile+16469313860,,94616304667#,,,,*047757# US+13017158592,,94616304667#,,,,*047757# US (Washington DC) Exploring the association of cannabis use with depression and suicidal behavior in youth Jesse D. Hinckley, MD, PhDDivision of Addiction Science, Treatment & Prevention, Department of Psychiatry, University of Colorado School of Medicine School of Medicine The co-occurrence MDD…

NIDA HIV Seminar Series: Social & Political Determinants of HIV Among People Who Use Drugs (July 31, 1pm ET)

NIDA HIV Seminar Series: July 31, 2024, 1pm ET

Join Dr. Ricky Bluthenthal, PhD, on July 31, 2024 (1-2pm ET) for the next NIDA HIV Seminar! Dr. Bluthenthal is a Distinguished Professor of Population and Public Health Sciences at the Keck School of Medicine at the University of Southern California. He conducts community-partnered research at the intersection of harm reduction and health disparities among people who use drugs. In this session, Dr. Bluthenthal will talk about social and political determinants of HIV among people who use drugs. Register for the seminar here!

New from the SIGs: Primary Care SIG Page Up, New Recording from Youth SIG

CTN SIG Updates

Primary Care SIG Update: New Page The Primary Care SIG has a new page up on the CTN Dissemination Library website, with information about the SIG’s objectives and when it meets. Check the page out here and reach out to Maria Prado (pradom@uw.edu) if you have any questions or want to participate in their webinar series (the 4th Monday of the month from 9-10 am PT!). New Recording from the Youth SIG Did you miss the Youth SIG’s recent webinar, Substance Use Among Black Adolescents – Maximizing Strengths and Overcoming…

News from the Ohio Valley Node

Node News

CTN-0129 Team presents at National Indian Health Board Conference Investigators and collaborating community partners for CTN-0129 “The Great Plains Initiative” presented a discussion panel about the study at the National Indian Health Board conference on May 22, 2024 in Rapid City, SD. The panel was moderated by Brynn Luger, PhD and included Lead Investigator Donald Warne, MD, MPH, T. John Winhusen, PhD, Gene Tyon, MA of Oaye Luta Okolakiciye, Barbara Dull Knife, BS of Wakanyeia Gluwitayan Otipi, and Ellen Durkin MSW of South Dakota Urban Indian Health. Allison Kelliher, MD…

News from the Greater Intermountain Node

Node News

Greater Intermountain Node (GIN) Medical Clinician, Jasmin Charles, MPAS, PA-C, has been awarded the 2024 Physician Associate (PA) of the Year by the American Academy of Physician Associates (AAPA). Read the AAPA PA of the Year Award announcement about Jasmin here. The AAPA PA of the Year Award honors PA’s who demonstrate exemplary service to the community; exemplify the PA profession’s philosophy of providing accessible, quality healthcare to all; and furthers the image of the profession in a positive, meaningful way. Jasmin is the Clinical Director of the SUPeRAD (Substance…

Webinar: Opioid Clinical Decision Support in Primary Care: CTN-0095 (1.5 CME/CE; June 26, 2024)

Opioid Clinical Decision Support in Primary Care: CTN-0095 webinar June 26, 2024

Join the Western States Node of the CTN and the Northwest and Pacific Southwest ATTCs for their next joint webinar, coming June 26, 2024, 11am-12:30pm PT! In this session, Opioid Clinical Decision Support in Primary Care: CTN-0095, presenters Stephanie Hooker, PhD, MPH (HealthPartners Institute), and Rebecca Rossom, MD, MS (HealthPartners Institute and PI of the CTN NorthStar Node), will discuss the design and implementation of Opioid Wizard, a clinical decision support tool embedded in the EHR for primary care clinicians. The goal of the Opioid Wizard tool is to help…

New in the Library (May – June 2024)

New in the Library

Here are the latest items added to the CTN Dissemination Library for May – June 2024 (this post will be updated as new items come in): “To prescribe or not to prescribe, that is the question”: Perspectives on opioid prescribing for chronic, cancer-related pain from clinicians who treat pain in survivorship. Bulls HW, et al. Cancer. 2024 Apr 3. doi: 10.1002/cncr.35299. PMID: 38567685. CTN-0115 Substance Use Among Black Adolescents – Maximizing Strengths and Overcoming Barriers in Substance Use Prevention. Aneni K. Youth Special Interest Group (SIG) webinar, May 2024. Wiidookaage’win:…

Update on CTN-0082

Protocol Update

The CTN-0082 primary outcomes article was recently featured in the NIDA HIV Research Program email newsletter: What predicts willingness to take PrEP among people who use opioids? A cross-sectional survey developed by NIDA’s Clinical Trials Network was given to 308 HIV-negative people who use opioids (PWUO) across eight Southern cities with high HIV incidence. Half had heard of PrEP, but only 4% had ever taken it. Investigators found that willingness to take daily oral PrEP and willingness to take long-acting injectable (LAI) PrEP were moderately high (69.16% and 62.02%, respectively). Educational attainment and…

Update on CTN-0097: Primary Outcomes Article Published!

Protocol Update

The primary outcomes article for CTN-0097, Surmounting Withdrawal to Initiate Fast Treatment with Naltrexone (SWIFT): Improving the Real-World Effectiveness of Injection Naltrexone for Opioid Use Disorder (NIH HEAL Initiative), is now available! Published in JAMA Network Open, the findings from the study suggest that starting people with opioid use disorder (OUD) on extended-release injectable naltrexone (XR-naltrexone) within 5-7 days of seeking treatment is more effective than the standard treatment method of starting within 10-15 days, but requires closer medical supervision. This rapid treatment protocol could make XR-naltrexone more viable as…

Update on CTN-0100 (RDD)

Protocol Update

During March, the CTN-0100 Project Team initiated a month-long BINGO challenge with the goal of boosting QA and participant tracking and retention across the 18 study sites. BINGO tasks encompassed completing all scheduled visits for the week, locating a missing participant, performing internal QA, addressing data queries, and conducting street/community outreach for an MIA participant. The Bellevue site of the New York Node (pictured) achieved “BINGO” first, just 18 days into the challenge! By the end of the month, 9 additional sites also achieved “BINGO.” We express our gratitude to…

Bringing the Latest Evidence-based Substance Use Disorder Treatments into Clinical Practice

NIDA CTN Dissemination Initiative

The National Institute on Drug Abuse Clinical Trials Network Dissemination Initiative (NIDA CTN DI) promotes the adoption of evidence-based practices and research on substance use disorders into clinical practice.  For one recent project, NIDA CTN DI staff partnered with nationally known subject-matter experts in opioid use disorder (OUD) and the Centers for Medicare & Medicaid Services (CMS) to create a four-part podcast series available for continuing medical education (CME) credit. The series, called Buprenorphine Initiation in the Emergency Department: Why, When, and How? takes hospital leaders and emergency department teams…

New in the Library (Apr – May 2024)

New in the Library

ATTENTION! The new CTN Directory is here! Published in April 2024, it has updated contact information for members of all 16 nodes, the Clinical Coordinating Center, and the Data and Statistics Center. You can find a link to it right on the CTN Dissemination Library’s home page as well as RIGHT HERE. Here are the latest items added to the CTN Dissemination Library for April – May 2024 (this post will be updated as new items come in): Rapid Initiation of Injection Naltrexone for Opioid Use Disorder: A Stepped-Wedge Cluster…

NIDA Celebrates 50 Years – Comments from NIDA Director Nora Volkow, MD

New from NIDA

NIDA Director Nora Volkow, MD, has a new commentary piece out in the American Journal of Psychiatry: Drugs and Addiction Science: NIDA Celebrates 50 Years of Research and Looks to the Future (published online May 6, 2024, doi: 10.1176/appi.ajp.20230880) From the piece: The National Institute on Drug Abuse (NIDA)—first established in 1974 as part of the Alcohol, Drug Abuse, and Mental Health Administration and in 1992 becoming part of the National Institutes of Health (NIH)—is the largest funder of research on drug use and addiction in the world. Over its 50-year…

News from the Southern Consortium Node

Node News

On April 29, 2024, the Southern Consortium Node granted the inaugural Outstanding Public Leadership Award to Sara Goldsby, Director of the South Carolina Department of Alcohol and Other Drug Abuse Services. (Pictured: Drs. Kelly Barth, Kathleen Brady, Connie Guille with Ms. Sara Goldsby.) The award was established to recognize state and local government officials who have made exceptional contributions to the advancement of policy and practice in the field of addiction. Ms. Goldsby has been a tireless advocate for South Carolinians struggling with addiction, leading the state’s response to the…

Artificial Intelligence in Medicine & Imaging (AIMI) Symposium 2024 (May 15, Free, @ Stanford and Online)

Machine learning and artificial intelligence are redefining the boundaries of medicine, unleashing potential like never before to ensure better health for all. Sponsored by the Stanford University Center for Artificial Intelligence in Medicine & Imagining (AIMI), the FREE AIMI Symposium serves as their flagship annual meeting, focusing on the pioneering developments and significant strides in AI that are shaping the future of healthcare. They will highlight cutting-edge research and methods, showcase current and emerging real-world clinical applications, and address critical issues related to fairness and societal impact.  This symposium serves…

AHSR 2024: Abstract Submission Deadline Extended to May 10!

AHSR 2024

AHSR is still accepting individual presentation and symposium abstracts for innovative and impactful research that moves the field of addiction forward. Abstracts must be submitted by the person who intends to present the study in the case of an individual presentation, and by the chair/moderator in the case of a symposium session. We anticipate that accepted abstracts will be published in a peer-reviewed journal. The deadline for all submissions is Friday, May 10, 2024, at 11:59 PM PT. The AHSR Early Career Investigator Award recognizes scholars with early achievements and exceptional promise for future contributions to addiction…

New in the Library (Mar – Apr 2024)

New in the Library

ATTENTION! The new CTN Directory is here! Published in April 2024, it has updated contact information for members of all 16 nodes, the Clinical Coordinating Center, and the Data and Statistics Center. You can find a link to it right on the CTN Dissemination Library’s home page as well as RIGHT HERE. Here are the latest items added to the CTN Dissemination Library for March – April 2024 (this post will be updated as new items come in):  Exemplar Hospital Initiation Trial to Enhance Treatment Engagement (EXHIT ENTRE): Protocol for…

News from the Ohio Valley Node

Node News

IMPROVE Studies in Progress!  In October 2023 the NIH IMPROVE initiative approved funds to conduct four projects under the overall leadership of Dr. John Winhusen, current Lead Investigator of the CTN 0080 MOMs study.  CTN investigators are preparing to conduct three research studies and one dissemination activity, described below:  CTN 0150: Personally-Tailored Opioid-overdose and Medication for opioid use disorder (MOUD) Education (TOME; LI – Winhusen, OVN): This study is an intent-to-treat, open-label, randomized controlled trial planning to (1) evaluate the ability of TOME to increase MOUD and opioid-overdose knowledge in…

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