What’s New in the CTN?
Updates from the NIDA National Drug Abuse Treatment Clinical Trials Network. Want to share some news about your protocol, node, publications or presentations, or other CTN-related work here and/or in the CTN Bulletin? Email us at ctnlib@uw.edu!
CTN Annual Scientific Meeting: October 21-23, 2024 – Poster submissions open!
The National Drug Abuse Treatment Clinical Trials Network (CTN) will hold its Annual Scientific Meeting celebrating the 25th Anniversary of the CTN on Monday-Wednesday, October 21-23, 2024. The meeting will be held at the Crystal Gateway Marriott in Arlington, Virginia. Registration and hotel information coming soon — on or before the week of July 29. Poster session information Sharing of the results, experiences, techniques, and observations from performing our trials is a critical and exciting part of the CTN experience. To that end, CTN members are encouraged to submit posters for…
New in the Library (June – July 2024)
Here are the latest items added to the CTN Dissemination Library for June – July 2024 (this post will be updated as new items come in): Extended-Release 7-Day Injectable Buprenorphine for Patients With Minimal to Mild Opioid Withdrawal. D’Onofrio G, et al. JAMA Network Open 2024;7(7):e2420702. The Potential Impact of Clinical Decision Support on Nonwaivered Primary Care Clinicians’ Prescribing of Buprenorphine. Olson AW, et al. Health Affairs Scholar 2023;1(4):qxad051. CTN-0076-Ot Barriers and Facilitators to Using a Clinical Decision Support Tool for Opioid Use Disorder in Primary Care: Insights from Clinicians…
Primary Care SIG Webinar: Are We There Yet? 25 Years of Research on Treating OUD in Primary Care (July 22, 12pm ET)
Join the CTN Primary Care SIG on July 22, 2024 (12-1pm EST) for their next webinar, featuring David Fiellin, MD from Yale School of Medicine presenting “Are we there yet? 25 years of research on treating OUD in primary care.” Please join the webinar here (no registration required).Passcode: 201068 Interested in presenting at a future Primary Care SIG meeting? Email Joe LeMaster at jlemaster@kumc.edu or Sebastian Tong at setong@uw.edu Posted July 15, 2024
Upcoming Youth SIG Webinars
The CTN Youth SIG is pleased to invite you to two upcoming presentations in 2024 (all dates are at 11am-12pm ET): Sept 20 – Dr. Sivabalaji Kaliamurthy Nov 15 – Dr. Velma Murry Both meetings can be accessed via Zoom: Zoom link: https://dartmouth.zoom.us/j/94616304667?pwd=MHhGUjBzcmVNUVVlV1IyT0hjR3YrUT09Meeting ID: 946 1630 4667Passcode: 047757
News from the Appalachian Node
Penn State Health and University of Maryland are two sites selected to work on the HEAL funded study looking at the effectiveness of GLP-1 agonists as adjunctive treatment for OUD, slated to begin recruitment in the Fall. Site PIs: Sarah Kawasaki and Aaron Greenblatt/Eric Weintraub. posted on July 5, 2024
News from the Western States Node: James L. Sorensen Award
CPDD honored Jim Sorensen (who served as an MPI for the Western States Node of the CTN) and made the first James L. Sorensen Distinguished Treatment and Service Mentor award to Jeffery Samet, MD for his scientific leadership and his mentorship of addiction medicine physicians. Dr. Sorensen’s widow (Laurel Koepernik) and Jim’s brothers (Roger and Bryan) hosted a reception to present the award to Dr. Samet. The annual award remembers Jim Sorensen’s contributions to CPDD, his many years of mentoring clinicians and investigators, and his leadership in the development of…
New from the CTN Translation & Implementation SIG
March & May Webinar Recordings Available Did you miss the March and/or May meetings of the CTN T&I SIG? No worries, the recordings are now available in the CTN Dissemination Library! March 2024: Multilevel Adaptive Implementation Strategies (MAISYs) In this webinar, Danny Almirall, a statistician and effectiveness implementation intervention scientist, discussed the need for multilevel, multicomponent implementation strategies from the perspective of implementation support professionals; and multilevel adaptive implementation strategies (MAISYs) as a potential solution. May 2024: The OUD Cascade of Care: Tailoring Pathways for Buprenorphine Treatment In this one,…
News from the Appalachian Node
The Appalachian Node has two new publications to report: Bulls HW, Hamm M, Wasilewski J, Olejniczak D, Bell SG, Liebschutz JM. “To prescribe or not to prescribe, that is the question”: Perspectives on opioid prescribing for chronic, cancer-related pain from clinicians who treat pain in survivorship. Cancer. 2024 Apr 3. doi: 10.1002/cncr.35299. PMID: 38567685. Jennings LK, Lander L, Lawdahl T, McClure EA, Moreland A, McCauley JL, Haynes L, Matheson T, Jones R, Robey TE, Kawasaki S, Moschella P, Raheemullah A, Miller S, Gregovich G, Waltman D, Brady KT, Barth KS. Characterization of peer…
CTN Youth SIG Webinar, July 19, 2024, 11am ET
The CTN Youth SIG is pleased to invite you to an upcoming presentation with two invited speakers: Presenters: Jesse D. Hinckley, MD, PhD and Chris Hammond, MH, PhD Friday, July 19th, 2024 (11:00 a.m.–12:00 p.m. ET) Join Zoom Meeting:https://dartmouth.zoom.us/j/94616304667?pwd=MHhGUjBzcmVNUVVlV1IyT0hjR3YrUT09 Meeting ID: 946 1630 4667Passcode: 047757One tap mobile+16469313860,,94616304667#,,,,*047757# US+13017158592,,94616304667#,,,,*047757# US (Washington DC) Exploring the association of cannabis use with depression and suicidal behavior in youth Jesse D. Hinckley, MD, PhDDivision of Addiction Science, Treatment & Prevention, Department of Psychiatry, University of Colorado School of Medicine School of Medicine The co-occurrence MDD…
NIDA HIV Seminar Series: Social & Political Determinants of HIV Among People Who Use Drugs (July 31, 1pm ET)
Join Dr. Ricky Bluthenthal, PhD, on July 31, 2024 (1-2pm ET) for the next NIDA HIV Seminar! Dr. Bluthenthal is a Distinguished Professor of Population and Public Health Sciences at the Keck School of Medicine at the University of Southern California. He conducts community-partnered research at the intersection of harm reduction and health disparities among people who use drugs. In this session, Dr. Bluthenthal will talk about social and political determinants of HIV among people who use drugs. Register for the seminar here!
New from the SIGs: Primary Care SIG Page Up, New Recording from Youth SIG
Primary Care SIG Update: New Page The Primary Care SIG has a new page up on the CTN Dissemination Library website, with information about the SIG’s objectives and when it meets. Check the page out here and reach out to Maria Prado (pradom@uw.edu) if you have any questions or want to participate in their webinar series (the 4th Monday of the month from 9-10 am PT!). New Recording from the Youth SIG Did you miss the Youth SIG’s recent webinar, Substance Use Among Black Adolescents – Maximizing Strengths and Overcoming…
News from the Ohio Valley Node
CTN-0129 Team presents at National Indian Health Board Conference Investigators and collaborating community partners for CTN-0129 “The Great Plains Initiative” presented a discussion panel about the study at the National Indian Health Board conference on May 22, 2024 in Rapid City, SD. The panel was moderated by Brynn Luger, PhD and included Lead Investigator Donald Warne, MD, MPH, T. John Winhusen, PhD, Gene Tyon, MA of Oaye Luta Okolakiciye, Barbara Dull Knife, BS of Wakanyeia Gluwitayan Otipi, and Ellen Durkin MSW of South Dakota Urban Indian Health. Allison Kelliher, MD…
News from the Greater Intermountain Node
Greater Intermountain Node (GIN) Medical Clinician, Jasmin Charles, MPAS, PA-C, has been awarded the 2024 Physician Associate (PA) of the Year by the American Academy of Physician Associates (AAPA). Read the AAPA PA of the Year Award announcement about Jasmin here. The AAPA PA of the Year Award honors PA’s who demonstrate exemplary service to the community; exemplify the PA profession’s philosophy of providing accessible, quality healthcare to all; and furthers the image of the profession in a positive, meaningful way. Jasmin is the Clinical Director of the SUPeRAD (Substance…
Webinar: Opioid Clinical Decision Support in Primary Care: CTN-0095 (1.5 CME/CE; June 26, 2024)
Join the Western States Node of the CTN and the Northwest and Pacific Southwest ATTCs for their next joint webinar, coming June 26, 2024, 11am-12:30pm PT! In this session, Opioid Clinical Decision Support in Primary Care: CTN-0095, presenters Stephanie Hooker, PhD, MPH (HealthPartners Institute), and Rebecca Rossom, MD, MS (HealthPartners Institute and PI of the CTN NorthStar Node), will discuss the design and implementation of Opioid Wizard, a clinical decision support tool embedded in the EHR for primary care clinicians. The goal of the Opioid Wizard tool is to help…
New in the Library (May – June 2024)
Here are the latest items added to the CTN Dissemination Library for May – June 2024 (this post will be updated as new items come in): “To prescribe or not to prescribe, that is the question”: Perspectives on opioid prescribing for chronic, cancer-related pain from clinicians who treat pain in survivorship. Bulls HW, et al. Cancer. 2024 Apr 3. doi: 10.1002/cncr.35299. PMID: 38567685. CTN-0115 Substance Use Among Black Adolescents – Maximizing Strengths and Overcoming Barriers in Substance Use Prevention. Aneni K. Youth Special Interest Group (SIG) webinar, May 2024. Wiidookaage’win:…
Update on CTN-0082
The CTN-0082 primary outcomes article was recently featured in the NIDA HIV Research Program email newsletter: What predicts willingness to take PrEP among people who use opioids? A cross-sectional survey developed by NIDA’s Clinical Trials Network was given to 308 HIV-negative people who use opioids (PWUO) across eight Southern cities with high HIV incidence. Half had heard of PrEP, but only 4% had ever taken it. Investigators found that willingness to take daily oral PrEP and willingness to take long-acting injectable (LAI) PrEP were moderately high (69.16% and 62.02%, respectively). Educational attainment and…
Update on CTN-0097: Primary Outcomes Article Published!
The primary outcomes article for CTN-0097, Surmounting Withdrawal to Initiate Fast Treatment with Naltrexone (SWIFT): Improving the Real-World Effectiveness of Injection Naltrexone for Opioid Use Disorder (NIH HEAL Initiative), is now available! Published in JAMA Network Open, the findings from the study suggest that starting people with opioid use disorder (OUD) on extended-release injectable naltrexone (XR-naltrexone) within 5-7 days of seeking treatment is more effective than the standard treatment method of starting within 10-15 days, but requires closer medical supervision. This rapid treatment protocol could make XR-naltrexone more viable as…
Update on CTN-0100 (RDD)
During March, the CTN-0100 Project Team initiated a month-long BINGO challenge with the goal of boosting QA and participant tracking and retention across the 18 study sites. BINGO tasks encompassed completing all scheduled visits for the week, locating a missing participant, performing internal QA, addressing data queries, and conducting street/community outreach for an MIA participant. The Bellevue site of the New York Node (pictured) achieved “BINGO” first, just 18 days into the challenge! By the end of the month, 9 additional sites also achieved “BINGO.” We express our gratitude to…
Bringing the Latest Evidence-based Substance Use Disorder Treatments into Clinical Practice
The National Institute on Drug Abuse Clinical Trials Network Dissemination Initiative (NIDA CTN DI) promotes the adoption of evidence-based practices and research on substance use disorders into clinical practice. For one recent project, NIDA CTN DI staff partnered with nationally known subject-matter experts in opioid use disorder (OUD) and the Centers for Medicare & Medicaid Services (CMS) to create a four-part podcast series available for continuing medical education (CME) credit. The series, called Buprenorphine Initiation in the Emergency Department: Why, When, and How? takes hospital leaders and emergency department teams…