CTN-0031: Stimulant Abuser Groups to Engage in 12-Step (STAGE-12): Evaluation of a Combined Individual-Group Intervention to Reduce Stimulant and Other Drug Use by Increasing 12-Step Involvement

Dennis M. Donovan, PhD
Co-Lead Investigator
Director, Alcohol and Drug Abuse Institute
University of Washington

Dennis Daley, PhD
Co-Lead Investigator
Chief, Addiction Medicine Services
Western Psychiatric Institute and Clinic

The primary objective of this protocol is to evaluate the degree to which a combined group and individual 12-Step facilitative intervention, Stimulant Abuser Groups to Engage in 12 -Step (STAGE-12), improves substance -related outcomes compared to treatment as usual (TAU) without STAGE-12 among stimulant abusers.  For this protocol, STAGE-12 will be integrated into treatment as usual.  The primary objective is to evaluate reduction in percent of days of stimulant use as measured by self-report.  This is a randomized, 2-group design comparing STAGE-12 integrated into TAU (STAGE-12 /TAU) to TAU without STAGE-12 for stimulant abusers receiving formal substance abuse treatment in participating community-based treatment programs (CTP).  A total of approximately 450 stimulant users seeking formal treatment, recruited from 10 CTPS, will be randomized.

Primary Findings

Findings were mixed with respect to the impact of integrating the STAGE-12 intervention into intensive outpatient drug treatment compared with treatment as usual on stimulant drug use. However, the results more clearly indicate that individuals in STAGE-12 had higher rates of 12-step meeting attendance and were engaged in more related activities throughout both the active treatment phase and the entire 6-month follow-up period than did those in treatment as usual.

Primary Outcomes Article: Donovan DM, et al. Stimulant Abuser Groups to Engage in 12-Step (STAGE-12): A Multisite Trial in the National Institute on Drug Abuse Clinical Trials Network. Journal of Substance Abuse Treatment 2012;44(1):103-114. [get article]

    Node Involvement

    Lead Node(s):

  • Pacific Northwest Node

  • All Participating Nodes:

  • Appalachian Tri-State Node
  • Florida Node Alliance
  • Ohio Valley Node
  • Pacific Northwest Node
  • Pacific Region Node
  • Southern Consortium Node
  • Texas Node
  • Western States Node