Lisa R. Metsch, PhD
Associate Professor, Dept. of Epidemiology and Public Health
University of Miami Miller School of Medicine
Project HOPE will evaluate the effectiveness of a brief intervention delivered to HIV-infected drug users recruited from the hospital setting in achieving viral suppression. The trial comprises: 1) an active patient navigator component: a strengths-based case management approach that includes motivation, physical escort to treatment, and face-to-face booster sessions; and 2) a passive incentives/contingency management component to further motivate and reinforce completion of target behaviors. The primary goal of the study is HIV viral suppression. In addition, the study will also determine linkage and retention in HIV primary care, linkage and retention in drug abuse treatment, and reduction in numbers of hospitalizations.
Among hospitalized patients with HIV infection and substance use, patient navigation with or without financial incentives did not have a beneficial effect on HIV viral suppression relative to nonsuppression or death at 12 months vs. treatment as usual. These findings do not support these interventions in this setting and indicate that other approaches are needed to improve HIV outcomes in this vulnerable population.
Primary Outcomes Article: Metsch LR, et al. Effect of Patient Navigation With or Without Financial Incentives on Viral Suppression Among Hospitalized Patients with HIV Infection and Substance Use: A Randomized Trial. JAMA 2016;316(2):156-170. [get article]
- CTN-0049-A-1: Examining the Patient Navigation Process for HIV and Substance Abuse Treatment
- CTN-0049-A-2: Utilization of the Electronic Medical Record to Assess and Predict 30-Day Readmission Risk Among HIV-Infected Inpatients Enrolled in CTN-0049
- CTN-0064: Linkage to Hepatitis C Virus (HCV) Care among HIV/HCV Co-infected Substance Users
All Participating Nodes: