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CTN Youth SIG: Watch the Recording from November’s Session
The recording from November 2025’s CTN Youth Special Interest Group webinar is now available in the CTN Dissemination Library! Advancing equity through implementation science in adolescent substance use prevention Culturally and contextually grounded preventive interventions can address upstream risk and protective factors to improve equity, but only if they are implemented in systems that serve underrepresented groups. This presentation from Cady Berkel, PhD (Arizona State University) shared findings a program of community based research conducted in partnership with multiple settings (e.g., pediatric primary care, family courts, corrections) to advance equitable access to evidence-based substance use prevention for adolescents and families. Dr. Berkel also discussed implementation science frameworks and designs to incorporate equity and accelerate the translation of research into practice. Watch the recording here! Posted on December 5, 2025
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New in the Library (November – December 2025)
Here are the latest items added to the CTN Dissemination Library for November – December 2025 (this post will be updated as new items come in): Advancing equity through implementation science in adolescent substance use prevention. Berkel C. Youth Special Interest Group (SIG) webinar, November 2025. Future pandemic preparedness: conceptualizing vaccine willingness in drug-using populations during COVID-19 in Southeastern U.S. cities. Orozco K, et al. Journal of HIV/AIDS & Social Services 2025 (in press). (CTN-0082) Posted on November 24, 2025.
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New in the Library (October – November 2025)
Here are the latest items added to the CTN Dissemination Library for October – November 2025 (this post will be updated as new items come in): Predicting willingness to use MOUD: An application of the theory of reasoned action and theory of planned-behavior. Lancaster C, et al. Journal of Drug Issues 2025 (in press). (CTN-0082) Overdose risk profiles in pregnancy: Latent class analysis of pregnant individuals with opioid use disorder. Cash E, et al. Journal of Substance Use and Addiction Treatment 2025 (in press). (CTN-0080) Impact of a brief personally tailored opioid-overdose and medication for opioid use disorder education intervention on naloxone acceptance in peripartum individuals: A secondary exploratory analysis. Lofwall MR, et al. Journal of Substance Use and Addiction Treatment 2025 (in press). (CTN-0150) Buprenorphine treatment for opioid use disorder in non–addiction specialty settings. Huebler S, et al. JAMA Network Open 2025;8(11):e2543543. Thresholds for adjunctive medication usage and probability of initiating injectable naltrexone. Rudolph KE, et al. Addiction 2025 (in press). (CTN-0097) Integrating x-waiver training for opioid use disorder into the nurse practitioner and physician assistance curricula. Moreland AD, et al. Journal of the American Association of Nurse Practitioners 2025;37(7):406-412. (CTN-0089) Implementation outcomes included in NIDA Clinical Trials Network (CTN) studies: A systematic review of studies conducted over 20 years. Gonzalez ST, et al. Journal of Substance Use and Addiction Treatment 2025 (in press). (multiple CTN studies) A longitudinal observational study with ecological momentary assessment and deep learning to predict non-prescribed opioid use, treatment retention, and medication nonadherence…
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New in the Library (September-October 2025)
Here are the latest items added to the CTN Dissemination Library for September – October 2025 (this post will be updated as new items come in): A scoping review of interventions addressing social determinants of health and their influence on opioid use disorder outcomes. Cousins SJ, et al. Drug and Alcohol Dependence 2025;276:112858. (CTN-0143) Leadership and team effectiveness for implementation in children’s mental health. Aarons G. Youth Special Interest Group (SIG) webinar, September 2025. Clinical decision support to increase provision of opioid use disorder services in primary care. Rossom R, Hooker S, Bart G. Webinar from the CTN Translation & Implementation SIG, September 2025. Posted October 8, 2025, updated October 13, 2025
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New in the Library (August-September 2025)
Here are the latest items added to the CTN Dissemination Library for August – September 2025 (this post will be updated as new items come in): Delivering Opioid Use Disorder Treatment Among American Indian and Alaska Native Adults During the COVID-19 Pandemic and Beyond: Facilitators and Barriers to Care. Hirchak KA, et al. Journal of Ethnicity in Substance Abuse 2025 (in press). (CTN-0096 and CTN-0118) Risks for Adverse Events by Sex and Age After Prescription Opioid Dose Reduction. Metz VE, et al. American Journal of Preventive Medicine 2025;108085 (in press). (CTN-0084) An Individual-Level Data Synthesis of Clinical Trials Network Studies to Examine the Impact of Psychosocial Treatments for Black People Who Use Cocaine and/or Opioids. Burlew AK, et al. Drug and Alcohol Dependence 2025 (in press). (primary outcomes for CTN-0125) “PrEP is Always on the Table”: Mixed Methods Study of Provider Willingness to Refer/Link Clients to PrEP in Community Sexual Health and Drug Use-Related Programs. Paschen-Wolff MM, et al. Journal of HIV/AIDS & Social Services 2025 (in press). (CTN-0082)
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New in the Library (July – August 2025)
Here are the latest items added to the CTN Dissemination Library for July – August 2025 (this post will be updated as new items come in): Exploring Clinical Profile and Treatment Outcome Differences Based on Baseline Smoking and Alcohol Co-Use Status Among Individuals Initiating Medication for Opioid Use Disorder Treatment. León G, et al. American Journal on Addictions 2025 (in press). (CTN-0027) Understanding the Characteristics and Comorbidities of Primary Care Patients with Risky Opioid Use: Baseline Data from the Multi-Site “Subthreshold Opioid Use Disorder Prevention” (STOP) Trial. Rostam-Abadi Y, et al. Journal of General Internal Medicine 2025 (in press). (CTN-0101) Suicidal Ideation in Adults with Opioid Use Disorder Treated with Buprenorphine-Naloxone versus Extended-Release Naltrexone. Rizk R, et al. American Journal of Drug and Alcohol Abuse 2025 (in press). (CTN-0051) Clinical Decision Support System for Primary Care of Opioid Use Disorder: A Randomized Clinical Trial. Rossom RC, et al. JAMA Internal Medicine 2025 (in press). (primary outcomes for CTN-0095) Why is Substance Use Missing from My Patient’s Problem List? CTN Research to Advance Screening, Prevention, and Treatment of Substance Use in Primary Care [commentary]. McNeely J, et al. Journal of Substance Use & Addiction Treatment 2025;209780 (in press). Research Agenda Evaluating Measurement-Based Care for Opioid Use Disorder Among Patients with Co-Occurring Depressive Disorders [opinion]. Ghitza UE. Frontiers in Psychiatry 2025;16:1624642. Early Change in Depressive Symptom Severity with Naltrexone-Bupropion Combination and its Association with Reduction in Methamphetamine Use in ADAPT-2 Trial. Jha MK, et al. Journal of Clinical Psychiatry 2025;86(3):25m15825. (CTN-0068)…
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New in the Library (June-July 2025)
Here are the latest items added to the CTN Dissemination Library for June – July 2025 (this post will be updated as new items come in): Note: if the links below are not working, try searching in the Library by title (we’re having some technical difficulties with caching!). Medications for Opioid Use Disorder: Predictors of Early Discontinuation and Reduction of Overdose Risk in U.S. Military Veterans by Medication Type. Hayes CJ, et al. Addiction 2025;120(1):138-151. (CTN-0142) Protocol Commentary for the SUCCESS (Successful Recruitment and Retention in a Randomized Controlled Trial of Pregnant Participants with Opioid Use Disorder) Study. Snyder AM, et al. Substance Use & Addiction Journal 2025:29767342251334490. (CTN-0080-A-1) Craving, Impulsivity, and Subsequent Methamphetamine Use with Naltrexone-Bupropion Versus Placebo: Findings from a Randomized Clinical Trial. Jha MK, et al. Journal of Addiction Medicine 2025 (in press). (CTN-0068) PILOT Peer Intervention Manual. Peer Intervention to Link Overdose Survivors to Treatment (PILOT). NIDA CTN Protocol 0107. Barth K, et al. NIDA Clinical Trials Network CTN-0107 Protocol Team. (CTN-0107) Using Structural Equation Modeling to Examine Barriers and Facilitators of HIV Pre-Exposure Prophylaxis Willingness and Length of Use in Men Who Have Sex with Men Who Use Substances in Eight Southern US Cities.Ertl M, et al. AIDS Patient Care and STDs 2025;39(6):245-256. (CTN-0082) Conducting an Implementation Intervention Study with American Indian and Alaska Native Communities: Methodological Considerations. Paschen-Wolff MM, et al. Contemporary Clinical Trials 2025;107992. (CTN-0096) Posted on June 23, 2025, updated July 9, 2025
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New in the Library (May-June 2025)
Here are the latest items added to the CTN Dissemination Library for May – June 2025 (this post will be updated as new items come in): “I Don’t Tell Anyone I Have Them”: Experiences with Opioid Stigma from the Perspective of Survivors Living with Chronic Cancer-Related Pain and Clinicians that Care for Them. Bell SG, et al. Journal of Pain 2025;32:105411. (CTN-0115) Posted on May 19, 2025.
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New in the Library (April – May 2025)
Here are the latest items added to the CTN Dissemination Library for April – May 2025 (this post will be updated as new items come in): Randomized, Placebo-Controlled Trial of Injectable Extended-Release Naltrexone and Injectable Extended-Release Buprenorphine for Cocaine Use Disorder (CURB-2): Study Rationale and Design. Trivedi MH, et al. Contemporary Clinical Trials 2025;154:107954. (CTN-0109) Identifying Alcohol Use Disorder and Problem Use in Adult Primary Care Patients: Comparison of the Tobacco, Alcohol, Prescription Medication and Other Substance (TAPS) Tool with the Alcohol Use Disorders Identification Test Consumption Items (AUDIT-C). Adam A, et al. Substance Use & Addiction Journal 2025 (in press). (CTN-0059) Repetitive Transcranial Magnetic Stimulation for Stimulant Use Disorders (STIMULUS): Protocol for a Multi-Site, Double-Blind, Randomized Controlled Trial. Atoui Z, et al. Addiction Science & Clinical Practice 2025;20:40. (CTN-0108) Impact of Recent Stimulant Use on Treatment Outcomes Amongst Individuals Initiating Medications for Opioid Use Disorders: Secondary Analysis of a Multisite Randomized Controlled Trial. Coles C, et al. Drug and Alcohol Dependence Reports 2025;15:100330. (CTN-0027) Exploring the Impact of Reduction in Methamphetamine Use on Sexual Risk Behaviors Among Men Who Have Sex with Men and Women: Findings from the ADAPT- 2 Trial. Okafor CN, et al. International Journal of Behavioral Medicine 2025 (in press). (CTN-0068) Posted April 24, 2025. Updated May 15, 2025.
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Prenatal Action for Taking Healthy Steps (PATHS) Toolkit: Spanish Materials Now Available!
The Prenatal Action for Taking Healthy Steps (PATHS) toolkit, developed out of protocol CTN-0080-A3 (led by the Ohio Valley Node), offers evidence-based educational resources about the use of medication to treat opioid use disorder (OUD) during and after pregnancy. The collection of resources was already available in two formats: one for general English speakers and another version adapted to be culturally and linguistically appropriate for American Indians & Alaska Natives. Now, added just last week, materials are now also available in Spanish! Resources include: Check out the complete PATHS Toolkit here! Posted on May 9, 2025