• AHSR 2024
    Events

    AHSR 2024: Abstract Submission Deadline Extended to May 10!

    AHSR is still accepting individual presentation and symposium abstracts for innovative and impactful research that moves the field of addiction forward. Abstracts must be submitted by the person who intends to present the study in the case of an individual presentation, and by the chair/moderator in the case of a symposium session. We anticipate that accepted abstracts will be published in a peer-reviewed journal. The deadline for all submissions is Friday, May 10, 2024, at 11:59 PM PT. The AHSR Early Career Investigator Award recognizes scholars with early achievements and exceptional promise for future contributions to addiction health services research. Continuing the tradition of recognizing and supporting the next generation of researchers, we will select up to six awardees to be recognized at the 2024 conference. Each awardee will receive a financial award to help offset conference travel and registration. Deadline to apply for the Early Career Investigator Award is Tuesday, May 21, 2024, at 11:59 PM PT. Find out more about the AHSR conference here!

  • New in the Library
    New in the Library

    New in the Library (Mar – Apr 2024)

    ATTENTION! The new CTN Directory is here! Published in April 2024, it has updated contact information for members of all 16 nodes, the Clinical Coordinating Center, and the Data and Statistics Center. You can find a link to it right on the CTN Dissemination Library’s home page as well as RIGHT HERE. Here are the latest items added to the CTN Dissemination Library for March – April 2024 (this post will be updated as new items come in):  Exemplar Hospital Initiation Trial to Enhance Treatment Engagement (EXHIT ENTRE): Protocol for CTN-0098B A Randomized Implementation Study to Support Hospitals in Caring for Patients with Opioid Use Disorder. Bart G, et al. Addiction Science & Clinical Practice 2024;19:29. National Institute on Drug Abuse Clinical Trials Network Meeting Report: Managing Patients Exposed to Xylazine-Adulterated Opioids in Emergency, Hospital and Addiction Care Settings. Perrone J, et al. Annals of Emergency Medicine 2024 (in press). Medication-Based Treatment Among Rural, Primary Care Patients Diagnosed with Opioid Use Disorder and Alcohol Use Disorder. Kan E, et al. Journal of Substance Use and Addiction Treatment 2024 (in press). CTN-0102 Implementing a Pharmacist-Integrated Collaborative Model of Medication Treatment for Opioid Use Disorder in Primary Care: Study Design and Methodological Considerations. McLeman B, et al. Addiction Science & Clinical Practice 2024;19:18. CTN-0116 Comparing Cannabis Use for Pain to Use for Other Reasons in Primary Care Patients. Ford MA, et al. Journal of the American Board of Family Medicine 2023;36(6):996-1007.

  • Node News
    Node News

    News from the Ohio Valley Node

    IMPROVE Studies in Progress!  In October 2023 the NIH IMPROVE initiative approved funds to conduct four projects under the overall leadership of Dr. John Winhusen, current Lead Investigator of the CTN 0080 MOMs study.  CTN investigators are preparing to conduct three research studies and one dissemination activity, described below:  CTN 0150: Personally-Tailored Opioid-overdose and Medication for opioid use disorder (MOUD) Education (TOME; LI – Winhusen, OVN): This study is an intent-to-treat, open-label, randomized controlled trial planning to (1) evaluate the ability of TOME to increase MOUD and opioid-overdose knowledge in Pregnant and Post-partum (PP) persons; and (2) evaluate the ability of TOME to decrease MOUD-related internalized stigma and expected difficulty in avoiding drug use.  CTN 0080 A-1: Successful Recruitment And Retention In A Randomized Controlled Trial Of Pregnant and Post-Partum People With Opioid Use Disorder (SUCCESS Study; LI – Smid, GIN). This ancillary study plans to perform qualitative interviews to identify successful strategies, facilitators, and barriers to recruiting pregnant individuals with opioid use disorder (OUD) and retaining them through the first year postpartum in the MOMs trial..  CTN 0080 A-2: Promoting Research with Mothers receiving OUD Treatment; a focus on Equity (PRoMOTE; LI – Schiff, NEC Node). This ancillary study plans to apply mixed-methods to investigate facilitators and barriers to treatment initiation of medications to treat opioid use disorder (MOUD), trial engagement, and study retention in CTN-0080, with a focus on race and equity.   CTN 0080 A-3: Improved Messaging Strategies for MOUD For Underserved Populations Of Pregnant And Postpartum…

  • CCC News
    Other

    News from the CCC

    We are pleased to share that Robrina Walker, PhD, who joined Emmes in May 2021 as a Project Leader, now serves as the Co-PI of the CCC, alongside CCC PI Eve Jelstrom. In addition to helping support and manage the CCC program/portfolio as a whole, Robrina’s direct study work includes being a Project Leader (the individual accountable for the CCC or DSC team’s support of a study) for CTN-0100 RDD (for both CCC & DSC), CTN-0121 Hi-SIRI (CCC & DSC), CTN-0102XR (CCC), and CTN-0144 (CCC). Robrina brings to Emmes nearly 25 years’ experience in clinical research in substance use disorder treatment trials funded by the Veteran’s Administration, NIAAA, and NIDA, 15 years of which have included the NIDA CTN. From 2008 to 2021, Robrina was a key Co-Investigator of the Texas Node (rebranded the Big South/West Node in 2020) and was responsible for scientific contributions and oversight, building out the network of investigators and study sites, and administrative/budgetary oversight. Robrina served in various roles over the years, including QA Monitor, Site PI, protocol development team member, Lead Investigator Team member, and mentor/supervisor to trainees and new investigators. In her final years at the node, Robrina served as Co-Lead Investigator and National Project Director for the groundbreaking CTN-0068 ADAPT-2 trial. Robrina is happy to add her experiences from the node side of the CTN to the support the CCC and DSC provides via the NIDA CCTN contracts.

  • Node News
    Node News

    News from the Appalachian Node

    Members of the Appalachian Node co-authored a manuscript with other CTN members that was published in the journal of Addiction Science & Clinical Practice. The title of the paper is “Characterization of Peer Support Services for Substance Use Disorders in 11 US Emergency Departments in 2020: Findings from a NIDA Clinical Trials Network Site Selection Process.” Authors are Lindsey Jennings; Laura Lander; Tricia Lawdahl; Erin McClure; Angela Moreland; Jenna McCauley; Louise Haynes; Timothy Matheson; Richard Jones; Thomas Robey; Sarah Kawasaki; Phillip Moschella; Amer Raheemullah; Suzette Miller; Gina Gregovich; Deborah Waltman; Kathleen Brady; Kelly Barth. This CTN collaboration looked at site surveys collected from 11 sites across the county with Emergency Department based Peer Support Services (PSS). There were important themes and similarities found among the 11 sites. First, at all but one site, PSSs remained available to patients in the ED, either in-person, virtually, or both, during the COVID-19 pandemic, suggesting their important integration as front-line health care workers, especially during the peak of the pandemic. PSSs were typically integrated into the medical care team, evidenced by a large majority of PSSs having access to the hospital EMR. These steps of integration of the PSS workflow into the medical team and medical record is an important step for efforts to advance PSS billing and reimbursement for services supported at the Federal level by the Medicaid 1115 Waiver. Secondly, PSSs at most ED sites initiated some contact with patients after ED discharge, suggesting that communication with patients outside of the…

  • AHSR 2024
    Events

    Addiction Health Services Research (AHSR) Conference 2024: Oct. 16-18

    The Addiction Health Services Research (AHSR) conference, held since 2005, brings together researchers, policymakers, and treatment providers to solve the problems of inequity, access, effectiveness, and implementation of addiction services. This conference has been hosted across the United States at leading institutions, including Weill Cornell Medicine, Brandeis University, the University of Utah School of Medicine, Brown University, and more. This year, the conference is hosted by the Center for Dissemination and Implementation (CDI), a Stanford University initiative, at the historic Palace Hotel in the beautiful and bustling city of San Francisco, near quintessential landmarks including the cable cars and Chinatown. The AHSR website is now live and registration is open!

  • Node News
    Node News

    News from the Health Systems Node

    2024 Emerging Leader Awards from the Committee of Presidents of Statistical Societies The Health Systems Node is pleased to announce and congratulate Jennifer Bobb, PhD Associate Scientific Investigator in the Biostatistics Division at Kaiser Permanente Washington Health Research Institute, on receiving one of the 2024 Emerging Leader Awards from the Committee of Presidents of Statistical Societies.  This award is given to up to 8 early career statisticians (international award eligible for all statisticians) who have demonstrated outstanding contributions to the field of statistical science.  Dr. Bobb was specifically recognized for her “significant methodological and applied contributions to the field of environmental biostatistics; for impactful research at the interface of cutting-edge statistical methods and real-world evidence to improve outcomes of people with substance use disorders; and for outstanding service to the profession.” Dr. Bobb leads the Methods Core of the Health Systems Node and was the lead statistician on the PROUD trial (CTN-0074), the Medical Cannabis study (CTN-0077), and several studies of substance use screening and assessment in primary care (CTN-0065 and CTN 00113).  The Health Systems Node is pleased to congratulate Dr. Bobb on this well-deserved honor.

  • Quarterly SC Meeting
    Events

    CTN Quarterly Steering Committee Meeting, April 16 – Updated start time: 2:45pm ET

    The next Clinical Trials Network (CTN) Quarterly Steering Committee Meeting will be held virtually on Tuesday, April 16, 2024, from 2:45 p.m.– 5:00 p.m. ET. Note: this is an updated start time! Join using this link | Download agenda If you would like to be added to the calendar invitation please email ctnsupport@leedmci.com. Also, while we will not convene in person this Spring, we are excited to announce our next in-person meeting will be held in the Fall of 2024 to coincide with the CTN 25th Anniversary. Please stay tuned for a formal announcement soon with the dates and location.

  • Uncategorized

    SAMHSA’s Final Rule on MOUD Published

    In February of this year, SAMHSA published a final rule allowing for the flexible use of medications to treat opioid use disorder in Opioid Treatment Programs that were enacted during the COVID-19 pandemic to become permanent. Highlights of this modification include: This rule (89 FR 7528) became effective on April 2, 2024, and providers need to be in compliance by October 2, 2024. The specifics and further details can be found on the Federal Register website.

  • Node News
    Node News

    News from the New York Node: Welcome Ryan D. McDonald!

    The New York Node is pleased to welcome Ryan D. McDonald as their new Node Coordinator. Ryan has worked at New York University Grossman School of Medicine in the Department of Population Health for over 12 years under Joshua Lee, MD, MSc. He joined Dr. Lee’s research team in 2011 as a Research Coordinator and since then has moved his way up to Project Manager, Program Manager, and most recently Program Director of research for the Department of Population Health’s Lee Lab. Most recently, Ryan managed a large multisite trial of the NIDA Justice Community Opioid Innovation Network (JCOIN) titled Long-acting Buprenorphine vs. Naltrexone Opioid Treatments in CJS-involved Adults (NCT04219540) study that seeks to compare the effectiveness of extended-release buprenorphine to extended-release naltrexone among criminal justice system -involved adults.