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CTN T&I SIG Session: A Pragmatic Measure of Context at the Organizational Level: The IFASIS (March 18, 9am PT)
Title: A Pragmatic Measure of Context at the Organizational Level: The Inventory of Factors Affecting Successful Implementation and Sustainment (IFASIS)Date/time: March 18, 2025, 9-10am PTSpeaker: Helene Chokron Garneau, PhD, MPH (Senior Research Scientist at Stanford University School of Medicine and co-Director of the Center for Dissemination and Implementation At Stanford (C-DIAS). Download/share the flyer (image file). Successful implementation and sustainment of interventions is heavily influence by context. Yet the complexity and dynamic nature of context make it challenging to connect and translate findings across implementation efforts, limiting potential replicability and utility. The Inventory of Factors Affecting Successful Implementation and Sustainment (IFASIS) was developed to be a pragmatic, quantitative, organizational-level assessment of contextual factors. The intention is to characterize context with a measure that may enhance replication and reproducibility of findings beyond single implementation case studies. This talk from the CTN Translation and Implementation (T&I) SIG will provide an overview of the development and validation of the IFASIS, as well as examples of its practical utility. To join the session, contact Elena Rosenberg-Carlson at rosenbee@stanford.edu
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Update from the CTN CCC and DSC
The CCC and DSC are pleased to announce a new resource on the CTN TPR Website: The CTN Sample Document Repository, a reference library of over 100 sample study documents developed by a working group of Node Coordinators and Project Directors from recent CTN studies. Sample study documents consist of training materials, recruitment and retention documents, as well as sample documents required for Protocol Review Board submission, among others. The CTN Sample Document Repository is a collaborative effort between the CTN Nodes, CCC, and DSC. Sample documents were developed and submitted by CTN Investigators and their study teams. Partnering with Dagmar Salazar from the CCC, a working group of Node Coordinators and Project Directors across four Nodes reviewed all submissions and collectively selected documents for inclusion in the Repository. The Repository is intended to serve as a valuable tool for project directors, study investigators, and especially new protocol teams leading CTN studies. Questions on specific documents should be directed to the corresponding contact person listed on the contact sheet posted to the Repository. The Repository can be found on the landing page of the CTN TPR website, by selecting “CTN Sample Document Repository” from the Main Menu Links. Many thanks to all who contributed to this effort, including all study teams who submitted their documents, and the working group members from the CTN Nodes past/present: Chantal Lambert-Harris, Phoebe Gauthier, Gina Gregovich, Sarah Farkas, Sarah Meyers-Ohki, Susan Sonne, Bethany McLeman, and Paulette Baukol.
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News from the Health System Node: Spotlight on Gwen Lapham, PhD, MPH, MSW
Spotlight on Health System Node Investigator – Gwen Lapham, PhD, MPH, MSW CTN studies often have many important secondary findings and Dr. Lapham, a CTN investigator in the Health Systems Node, has been making sure these get published rapidly. In 2024, Dr. Lapham led a paper on Year 3 outcomes of the PROUD Trial (CTN-0074) in JAMA Network Open, showing that the benefit of the PROUD nurse care manager intervention more than doubled during year 3 (compared to years 1-2 in the main results paper) with significant benefit in 4 of 6 health systems (compared to 2 in main results) suggesting that main results were early in implementation. Dr. Lapham, who led the CTN-0077 study (Medical Cannabis in EHRs), also oversaw 2 secondary papers this year, including one in the Journal of General Internal Medicine that showed the prevalence of cannabis use disorder increased with greater frequency of cannabis use reported by patients in the clinical setting. She also led a paper for CTN-140 published in the Journal of Addiction Medicine that identified predictors of participation among pregnant individuals who use cannabis in Kaiser Permanente Northern California’s Early Start program – a prenatal substance use assessment, counseling, and treatment program. The study found most pregnant individuals with prenatal cannabis use engaged in the program, though opportunities to improve care gaps remain. CTN-0074: Nurse Care Management of Opioid Use Disorder Treatment After 3 Years: A Secondary Analysis of the PROUD Cluster Randomized Clinical Trial. Lapham GT, Hyun N, Bobb JF, Wartko PD, Matthews…
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News from the Appalachian Node
The Appalachian Node has received a notice of award for funding for the next seven years (FY25 – FY32). We are excited to welcome to our newest partners, University of Maryland Baltimore and the PATH Network.
