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NIDA Research in Addiction Medicine (RAMS) Program – Apply Now!
The RAMS Program has opened up recruitment for its 14th cohort of Addiction Medicine and Addiction Psychiatry fellows interested in pursuing research! If you know of anyone who would benefit from our program, please share this information with them! Research in Addiction Medicine (RAMS) is a two-year supplemental program to one’s Addiction Medicine or Addiction Psychiatry fellowship and open to fellows who are considering a future academic research dimension in their career. For those enrolled in a one-year fellowship, we are looking for individuals who plan to enter into an academic position. AMS is funded by a grant from the National Institute on Drug Abuse (NIDA). Co-Directors are Drs. Patrick O’Connor (Yale School of Medicine) and Jeffrey Samet (Boston University Schools of Medicine & Public Health), and the Associate Director is Dr. E. Jennifer Edelman (Yale School of Medicine). Please see the official RAMS Program brochure for additional information. Key dates Please contact Jules Canfield, RAMS Program Manager, with your intention to apply and if you have any questions. More information, including Scholar & mentor applications, are available on the RAMS Program website. Posted on June 30, 2025.
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New from CTN-0107: PILOT Peer Intervention Manual
CTN-0107, the Peer Intervention to Link Overdose Survivors to Treatment (PILOT) trial, is a 3-site, randomized controlled trial using Peer Recovery Coaches trained in FORCE (FAVOR Overdose Recovery Coaching Evaluation), who will engage with opioid overdose survivors in the emergency department to get permission to contact them. The protocol team recently submitted the PILOT manual used by peers working on the study for inclusion in the CTN Dissemination Library. The manual provides materials to be used during peer training, reference materials to be used during the implementation of the clinical trial, and reference material for supervision. At the end of the study, the manual will be revised with input from participating peers and a revised manual will be developed for use in any follow-up studies. The manual contains sections on the background of the PILOT study and intervention, what PILOT peers do in the study (engagement/re-engagement, peer coaching, transition and termination of the intervention), other things peers know and do in the PILOT study (study documentation, supervision, self-care and support, safety), and an array of tools and FAQs for peer participants. Check out the PILOT manual here! Posted on June 30, 2025.
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CTN-0100 Study Reaches Recruitment Milestone
The CTN-0100 team is pleased to announce that the study reached its recruitment goal for the Discontinuation Phase (and the study overall) in May. The final participant was successfully randomized in June, marking the end of recruitment after four years of sustained effort! Over the course of the study, all 18 participating sites contributed to an extraordinary achievement: at least one participant was randomized for every calendar day during the four-year recruitment period. Despite challenges such as medication and app disruptions, the research teams demonstrated exceptional persistence and consistency. In total, 1,140 participants were randomized into the Retention Phase and 376 into the Discontinuation Phase. Congratulations to all involved in reaching this significant study milestone! Posted June 27, 2025
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News from the Greater Intermountain Node
Daniel Deykin Award for Outstanding Mentor Greater Intermountain Node Co-Principal Investigator Adam J. Gordon, MD, MPH, FACP, DFASAM, has been awarded the 2024 Health Services Research (HSR) Daniel Deykin Award for Outstanding Mentor by the U.S. Department of Veterans Affairs. This prestigious award recognizes HSR researchers who demonstrate exceptional commitment to mentoring the next generation of researchers, particularly by fostering an understanding of the critical perspectives of policymakers, Veterans, and other VA stakeholders. Learn more about the award here. Shauna Filion Panelist at CPDD Shauna Filion, the Greater Intermountain Node’s community representative on the CTN’s Community Representative Council (CIRCL), recently served as a panelist at the 2025 College on Problems of Drug Dependence (CPDD) conference during the “Learning from Those with Lived Experience” session. Shauna shared powerful insights on the value of lived experience and emphasized the importance of removing stigma in our interactions with both patients and research participants. Greater Intermountain Node Monthly Newsletter Stay up to date with the latest from the Greater Intermountain Node through our monthly newsletter, GIN Monthly. Each issue features research highlights, network news, and more. You can find the latest issue here and sign up for future newsletters here. Posted on June 13, 2025
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CTN Youth SIG Webinar: Neural Substrates of Risk-Reduction Interventions for Adolescents (July 18, 2025, 11am ET)
The CTN Youth SIG is pleased to invite you to an upcoming presentation/webinar: Neural Substrates of Risk-Reduction Interventions for Adolescents Friday, July 18th, 2025 (11:00 a.m.–12:00 p.m. ET) Presenter: Uma Rao, MDProfessor of Psychiatry and Human Behavior, Pediatrics, and Psychological Science at University of California, Irvine (UCI); Director of Education and Research in Psychiatry, Children’s Hospital of Orange County (CHOC) Adolescence is characterized by increased experimentation, which is helpful in the progression towards autonomy but also increases vulnerability to psychopathology. A temporal disassociation in the maturation of “socio-emotional” (reward) and “cognitive-control” (self-regulation) neural systems creates a period of poor decision-making and heightened vulnerability to risk-taking (reward-seeking) behavior with the onset of puberty. This presentation describes whether neural circuitry changes governing adolescent decision-making can be used to improve intervention programs seeking to deter risky behaviors, especially among African Americans who are disproportionately impacted by their negative consequences. Register for the Youth SIG webinar here! About the presenter: Dr. Uma Rao, is Professor of Psychiatry and Human Behavior at UC Irvine. Her research is focused on adolescent mood and substance use disorders, including neurobiological and psychosocial predictors of first onset and longitudinal clinical course of these disorders among at-risk youth (especially early-life adversity). In addition, she is involved in translational intervention research, examining biopsychosocial predictors of response to pharmacological and psychosocial interventions for these conditions. Posted on June 13, 2025.
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Ohio Valley Node Summer Speaker Series: Endocannabinoid Regulation of Repeated Stress-Cocaine Interactions (July 9, 12pm ET)
Join the University of Cincinnati College of Medicine Center for Addiction Research, part of the CTN Ohio Valley Node, is hosting a Summer Speaker Series. The series will highlight cutting-edge UC addiction research and UC-community collaborations related to prevention and treatment. The next session in the series will be held on July 9: Endocannabinoid Regulation of Repeated Stress-Cocaine Interactions July 9, 2025, 12-1pm ET Host: T. John Winhusen, PhD, University of Cincinnati Presenter: Jayme McReynolds, PhD Assistant Professor of Pharmacology,Department of Pharmacology, Physiology, & NeurobiologyUniversity of Cincinnati Register here!
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Submit Your Paper for the CTN 25th Anniversary Special Issue of JSAT!
To commemorate the 25th anniversary of the Clinical Trials Network, a special issue of the Journal of Substance Use and Addiction Treatment (JSAT) is being developed to highlight the remarkable contributions made across the network over the past 25 years. The journal is currently accepting submissions in the following categories: Interested in contributing? Please contact Mitchell Garets, MSW, at mitchell.garets@hsc.utah.edu from the Greater Intermountain Node for submission guidelines or any questions. While submissions will be accepted through Fall 2025, we encourage early contributions to support planning and review.