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New in the Library (August-September 2025)
Here are the latest items added to the CTN Dissemination Library for August – September 2025 (this post will be updated as new items come in): Delivering Opioid Use Disorder Treatment Among American Indian and Alaska Native Adults During the COVID-19 Pandemic and Beyond: Facilitators and Barriers to Care. Hirchak KA, et al. Journal of Ethnicity in Substance Abuse 2025 (in press). (CTN-0096 and CTN-0118) Risks for Adverse Events by Sex and Age After Prescription Opioid Dose Reduction. Metz VE, et al. American Journal of Preventive Medicine 2025;108085 (in press). (CTN-0084) An Individual-Level Data Synthesis of Clinical Trials Network Studies to Examine the Impact of Psychosocial Treatments for Black People Who Use Cocaine and/or Opioids. Burlew AK, et al. Drug and Alcohol Dependence 2025 (in press). (primary outcomes for CTN-0125) “PrEP is Always on the Table”: Mixed Methods Study of Provider Willingness to Refer/Link Clients to PrEP in Community Sexual Health and Drug Use-Related Programs. Paschen-Wolff MM, et al. Journal of HIV/AIDS & Social Services 2025 (in press). (CTN-0082)
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CTN Community Representation Council Meeting Summary (June 2025)
The CTN Community Representative Council (CIRCL) is a collaborative of the national CTN that comes together bimonthly to courageously share what’s happening in their communities. This brief is an overview of topics discussed at this meeting and is not an exhaustive review. Download/share a PDF of the brief. The thoughts and experiences herein are those of CIRCL members and do not represent the National Institute on Drug Abuse or the Clinical Trials Network. The voices empowered by CIRCL are intended to drive research and clinical efforts in the CTN and across the US. The following themes and discussions were highlighted during this meeting: Trends in substance use/public health: Challenges advocating for harm reduction in communities Interventions supporting families and blue-collar tradespersons critical Discontinuation of critical services and supplies due to funding challenges and changing priorities at federal and local levels Non-traditional approaches to provide treatment and harm reduction services Posted on August 18, 2025
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News from the Appalachian Node
We are pleased to welcome Donnie Young and David Sternberg as the newest members of the Appalachian Node Community Advisory Board. Both are affiliated with our team at the University of Maryland, Baltimore, and bring valuable expertise to our collaborative efforts. Posted on August 18, 2025
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New in the Library (July – August 2025)
Here are the latest items added to the CTN Dissemination Library for July – August 2025 (this post will be updated as new items come in): Exploring Clinical Profile and Treatment Outcome Differences Based on Baseline Smoking and Alcohol Co-Use Status Among Individuals Initiating Medication for Opioid Use Disorder Treatment. León G, et al. American Journal on Addictions 2025 (in press). (CTN-0027) Understanding the Characteristics and Comorbidities of Primary Care Patients with Risky Opioid Use: Baseline Data from the Multi-Site “Subthreshold Opioid Use Disorder Prevention” (STOP) Trial. Rostam-Abadi Y, et al. Journal of General Internal Medicine 2025 (in press). (CTN-0101) Suicidal Ideation in Adults with Opioid Use Disorder Treated with Buprenorphine-Naloxone versus Extended-Release Naltrexone. Rizk R, et al. American Journal of Drug and Alcohol Abuse 2025 (in press). (CTN-0051) Clinical Decision Support System for Primary Care of Opioid Use Disorder: A Randomized Clinical Trial. Rossom RC, et al. JAMA Internal Medicine 2025 (in press). (primary outcomes for CTN-0095) Why is Substance Use Missing from My Patient’s Problem List? CTN Research to Advance Screening, Prevention, and Treatment of Substance Use in Primary Care [commentary]. McNeely J, et al. Journal of Substance Use & Addiction Treatment 2025;209780 (in press). Research Agenda Evaluating Measurement-Based Care for Opioid Use Disorder Among Patients with Co-Occurring Depressive Disorders [opinion]. Ghitza UE. Frontiers in Psychiatry 2025;16:1624642. Early Change in Depressive Symptom Severity with Naltrexone-Bupropion Combination and its Association with Reduction in Methamphetamine Use in ADAPT-2 Trial. Jha MK, et al. Journal of Clinical Psychiatry 2025;86(3):25m15825. (CTN-0068)…
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News from the Pacific Northwest Node: CTN-0139 Update
Congratulations to the CTN-0139 Co-Care PRaCTICE study sites’ RC and RA on your dedication and efforts to meet the recruitment and enrollment goal. This is to acknowledge your willingness to go the extra mile while attending to the patient participants’ needs and responding to their requests. Thank you for all that you do to create success! Posted on August 7, 2025.
