The CTN-0082 primary outcomes article was recently featured in the NIDA HIV Research Program email newsletter: What predicts willingness to take PrEP among people who use opioids? A cross-sectional survey developed by NIDA’s Clinical Trials Network was given to 308 HIV-negative people who use opioids (PWUO) across eight Southern cities with high HIV incidence. Half had heard of PrEP, but only 4% had ever taken it. Investigators found that willingness to take daily oral PrEP and willingness to take long-acting injectable (LAI) PrEP were moderately high (69.16% and 62.02%, respectively). Educational attainment and having engaged in condomless vaginal sex predicted willingness to take oral PrEP, whereas only educational attainment predicted willingness to take…

During March, the CTN-0100 Project Team initiated a month-long BINGO challenge with the goal of boosting QA and participant tracking and retention across the 18 study sites. BINGO tasks encompassed completing all scheduled visits for the week, locating a missing participant, performing internal QA, addressing data queries, and conducting street/community outreach for an MIA participant. The Bellevue site of the New York Node (pictured) achieved “BINGO” first, just 18 days into the challenge! By the end of the month, 9 additional sites also achieved “BINGO.” We express our gratitude to all CTN-0100 sites for their dedication to this project. Download a copy of the BINGO sheet here!

In June, the CTN-0100 Project Team launched a month-long BINGO challenge aimed at boosting recruitment and retention across the 18 study sites. BINGO squares included hitting (or exceeding!) randomization targets for the month, reuniting with a missing participant, completing two randomizations in one day, and establishing a relationship with a new referring partner. The Operation PAR site (pictured) from the Florida Node Alliance was the first site to “BINGO,” just 6 days into the challenge! Five additional sites achieved “BINGO” by the end of the month. We thank all of the CTN-0100 sites for their continued diligence on this project! Check out the BINGO sheet used for this challenge here!…

March 15, 2023 CTN-0139, the Collaborative Care for Polysubstance use in Primary Care Settings (Co-Care) Trial, is studying a collaborative care intervention for polysubstance use involving opioids and/or stimulants, in adult primary care patients. Collaborative care is a team-based approach to managing chronic conditions that has been effective for depression and other behavioral health conditions, and has the potential to transform the delivery of substance use treatment in primary care settings. This HEAL-funded CTN trial will test the Co-Care model versus enhanced usual care to reduce substance use and improve substance use-related functioning.  The study will be conducted at 5 primary care sites (FQHCs and FQHC look-alikes).  A pilot study…

December 8, 2022 In November, the CTN-0100 Project Team launched a month-long BINGO challenge aimed at boosting recruitment across the 18 study sites. BINGO squares included hitting (or exceeding!) randomization targets for the month, reuniting with a missing participant, and completing internal QA. The Adapt site from the Western States Node and the SSTAR site from the New England Consortium Node were the first sites to “BINGO”, just 16 days into the challenge (see photos of the winning team below)! 7 additional sites achieved “BINGO” by the end of the month. We thank all of the CTN-0100 sites for their continued diligence on this project. Check out the BINGO sheet…