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Hybrid Event for Northern New Englanders: Addressing the Intersection of Pain Management and Opioid Use, September 29, 2023
The New England Opioid Response Network and Northeast Node of the National Drug Abuse Treatment Clinical Trials Network are pleased to bring together experts in the fields of pain and opioid use at a Regional Summit to be held in Concord, New Hampshire, on Friday, September 29, 2023. This event is intended for Northern New England audiences (Maine, New Hampshire, and Vermont). We invite all who provide care to patients that experience pain (acute or chronic), use opioids, or have opioid use disorder, to attend. This interdisciplinary team-based training will provide evidence-based solutions to managing pain and opioid use. In-person attendance is encouraged but limited – register now to reserve your seat! Virtual attendance is also an option, but may not be as rewarding. Interdisciplinary continuing education credits will be available (see details in registration). The content for this Summit was developed by leadership at our Node and our New England ORN team at Brown University. For more information & to register, please visit the summit website. Posted August 25, 2023
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NIDA HIV Research Program Seminars, September and October 2023
Please join the NIDA HIV Research Program (HRP) for more thought-provoking events coming this fall. First, on Wednesday, September 20, 2023 from 1:00pm to 4:00pm, we are holding a symposium led by recipients of Avenir Award Program (DP2) grants (PAR-23-125). Topics include the effects of opioids on HIV persistence across tissues, rethinking how we collect information to reduce overdose deaths, HIV and substance use comorbidity, developing IFN-modulated vaccines and vulnerabilities of HIV-1 escape from neutralizing antibodies. You can find more detailed information and the Avenir speaker’s list here. Registration is now open. Then, on Wednesday, October 25 at 11:00 a.m. EST we continue our NIDA HIV Seminar Series with the presentation “Long-Acting ART for Vulnerable Populations: Practical Considerations” with speakers Monica Gandhi, MD, MPH, and Katerina Christopoulos, MD, MPH, both from the University of California, San Francisco (UCSF). Register here. Posted August 17, 2023
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Webinar: Not Too Much, Not Too Often, and Not Too Many: The Results of the First Large-Scale International Project to Develop Lower-Risk Gambling Guidelines (September 6, 11am PT)
September 6, 2023 | 11:00am-12:30pm PT | Register here! Advice about how to gamble “responsibly” is widely promoted in many jurisdictions. However, until now, there has been no evidence-based, specific advice for people who gamble who want to reduce their risk of gambling harms. In 2016, the Canadian Centre on Substance Use and Addiction began the first large scale international, comprehensive, multimodal project to develop evidence based Lower-Risk Gambling Guidelines (LRGGs). Borrowing the same collaborative, evidence-driven approach used to develop the nation’s Low Risk Alcohol Drinking Guidelines, the LRGG initiative produced a set of workable, evidence-based quantitative limits on gambling behavior to help people make informed decisions about their gambling. This project included collaboration with researchers in eight other countries, analysis of epidemiological data from over 60,000 people who gamble, consultation with a pan- Canadian, multi-sectorial advisory committee made up of over 20 members, input from over 10,000 regular people who gamble via a national online survey, and qualitative data obtained from focus groups and interviews. This presentation from David Hodgins, PhD and Matthew Young, PhD will describe key deliverables from the LRGG project including the lower-risk limits for expenditure, frequency and number of types of games. It will also present a self-assessment quiz, a suite of posters and other knowledge mobilization tools that are freely available to those who with use or promote the guidelines (https://www.gamblingguidelines.ca). 1.5 CME or CE credits available. For more information on types of credits and accreditation, view the flyer. Sponsored by the Northwest and Pacific Southwest Addiction Technology…
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Virtual Xylazine Discussion Forum for CTN Investigators: September 26, 4pm ET
Join the Center for the Clinical Trials Network (CCTN) on Tuesday, September 26, 2023 from 4:00-5:30pm ET for a virtual Xylazine Discussion Forum for CTN investigators. Speakers Jeanmarie Perrone, MD (University of Pennsylvania) and Rachel Haroz, MD (Cooper University and Rowan University) will highlight the emerging threat of xylazine in the U.S. illicit drug supply, summarize emerging practices for treating people taking xylazine-adulterated opioids, and discuss research gaps and opportunities identified in a recent meeting of experts convened by NIDA. CTN researchers will be encouraged to participate in discussion and Q&A. View the recordings from this event here! Posted August 14, 2023, Updated September 2023
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New in the CTN Library (July-August 2023)
This post will contain a running list of all items added to the CTN Dissemination Library in July-August 2023. Castillo F, et al. Risks of Returning to Opioid Use at Treatment Entry and Early in Opioid Use Disorder Treatment: Role of Non-Opioid Substances. Drug and Alcohol Dependence 2023 (in press). CTN-0027, CTN-0030, CTN-0051 Parchman ML, et al. Supporting Practice Facilitators in a Learning Health Care System [commentary]. Permanente Journal 2023:23.035 Kidd JD, et al. Sexual Orientation Differences Among Men in a Randomized Clinical Trial of Extended-Release Naltrexone and Bupropion for Methamphetamine Use Disorder. Drug and Alcohol Dependence 2023; 250:110899. (CTN-0068) Trombello JM, et al. Psychometrics of the Concise Health Risk Tracking Self-Report (CHRT-SR16) Assessment of Suicidality in a Sample of Adults with Moderate to Severe Methamphetamine Use Disorder: Findings from the ADAPT-2 Randomized Trial. Neuropsychiatric Disease and Treatment 2023; 19:1443-1454. (CTN-0068)
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Update on CTN-0100 (RDD)
In June, the CTN-0100 Project Team launched a month-long BINGO challenge aimed at boosting recruitment and retention across the 18 study sites. BINGO squares included hitting (or exceeding!) randomization targets for the month, reuniting with a missing participant, completing two randomizations in one day, and establishing a relationship with a new referring partner. The Operation PAR site (pictured) from the Florida Node Alliance was the first site to “BINGO,” just 6 days into the challenge! Five additional sites achieved “BINGO” by the end of the month. We thank all of the CTN-0100 sites for their continued diligence on this project! Check out the BINGO sheet used for this challenge here! Posted July 26, 2023
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Recording available for June’s CTN Webinar on FDA Basics & Essential Regulatory Compliance
New webinar recording available: Research 101 Session 2: FDA Basics & Essential Regulatory Compliance Description:This webinar outlines the basics of FDA oversight and reviews other essential regulatory activities to successfully keep a study in compliance, including ongoing management and reporting requirements. The regulatory portion reviews essential regulatory activities, such as IRB approvals and informed consent requirements. Lastly, there is a discussion of current challenges and best practices when working on regulatory compliance. Check out the recording here! Posted July 7, 2023
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NIH Research Opportunity Announcements for N CREW Program (due Nov 1)
NIH has published two Research Opportunity Announcements (ROAs) for the HEAL-funded Native Collective Research Effort to Enhance Wellness (N CREW) Program, available on the N CREW Website. Applications are due Nov 1. Questions about this opportunity can be directed to NCREW@nih.gov. Additional information is also available on the N CREW Website. For more information, a Technical Assistance webinar will be held on Thursday, July 27th from 12:00 – 1:30 pm ET (click here to register). We encourage you to send any questions or comments about the ROAs and/or application process in advance of the webinar by emailing ncrew@nih.gov. Information on future webinars, questions and answers, and other information on the N CREW Program can be found at heal.nih.gov/ncrew. Posted July 10, 2023
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Science of D&I Conference: Call for Abstracts Open
AcademyHealth and the National Institutes of Health are once again convening the growing D&I science community for the 16th Annual Conference on the Science of Dissemination and Implementation in Health. The 16th Annual Conference theme is “Raising Expectations for D&I Science: Challenges and Opportunities”. The abstract solicitation and conference structure have been designed to focus our thinking and discussion on the highest priorities for dissemination and implementation science now and in the future to help optimize health and health care in the U.S. and globally. Does this sound like your work? Submit your abstract today! Abstracts due by July 18, 2023, at 5pm ET! Posted June 16, 2023
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NIDA HIV Seminar Series: Ending the HIV Epidemic in the U.S. (July 26, 1pm ET)
Join the NIDA HIV Research Program in welcoming Bohdan Nosyk, PhD, Associate Professor and St. Paul’s Hospital CANFAR Chair in HIV/AIDS Research at Simon Fraser University, for the next installment of the NIDA HIV Seminar Series titled “Ending the HIV/AIDS Epidemic in the US: How Do We Intervene to Meet Our Ambitious Goals?” Bohdan Nosyk is an Associate Professor and St. Paul’s Hospital CANFAR Chair in HIV/AIDS Research at the Faculty of Health Sciences, and leads the Health Economic Research Unit at the Center for Health Evaluation & Outcome Sciences. Dr. Nosyk’s research seeks to inform complex policy decisions surrounding the prevention and management of HIV/AIDS and substance use disorders. He has led population-level evaluations in these disease areas in China, in the state of California and across urban centers in the US, and locally in British Columbia. He combines simulation modeling methods and cost-effectiveness analyses with econometric and biostatistical analyses of health administrative data to address these issues. Dr. Nosyk’s teaching interests are in the areas of health economic evaluation and health services research. Register here!
